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\n \u57fa\u4e8e\u4ee5\u4e0a\u7279\u6027\uff0c\u7814\u7a76\u8005\u8ba4\u4e3aMSC\u53ef\u4ee5\u51cf\u8f7b\u6025\u6027\u80ba\u635f\u4f24\uff0c\u6291\u5236\u65b0\u51a0\u75c5\u6bd2\u8bf1\u5bfc\u7684\u7ec6\u80de\u4ecb\u5bfc\u7684\u708e\u75c7\u53cd\u5e94\uff08\u56fe\u4e00\uff09\u3002\u6b64\u5916\uff0c\u7531\u4e8eMSC\u7f3a\u5931\u65b0\u51a0\u75c5\u6bd2\u8fdb\u5165\u7ec6\u80de\u65f6\u6240\u9700\u7684ACE2\u53d7\u4f53\uff0c\u56e0\u6b64\uff0cMSC\u5bf9\u65b0\u51a0\u75c5\u6bd2\u611f\u67d3\u5177\u6709\u62b5\u6297\u529b\u3002<\/span>\n <\/section>\n
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\n $\"\u56fe\u7247\"$ \n <\/section>\n
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\n \u4e34\u5e8a\u7814\u7a76\u8fdb\u5c55<\/strong><\/span>\n <\/section>\n <\/section>\n
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\n \u53e6\u4e00\u9879\u5728\u4e2d\u56fd\u5f00\u5c55\u7684\u5bf9\u5e38\u89c4\u6cbb\u75977-10\u5929\u540e\u65e0\u6539\u5584\u7684\u65b0\u51a0\u91cd\u75c7\u60a3\u8005\u8f93\u6ce8\u4eba\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08hUC-MSC\uff09\u7684\u5c0f\u578b\u4e34\u5e8a\u8bd5\u9a8c\u3002\u572841\u4f8b\u5165\u7ec4\u7684\u60a3\u8005\u4e2d\uff0c12\u4f8b\u63a5\u53d7\u7ec6\u80de\u8f93\u6ce8\uff0c29\u4f8b\u63a5\u53d7\u5e38\u89c4\u62a4\u7406\u6cbb\u7597\u3002\u63a5\u53d7hUC-MSC\u8f93\u6ce8\u768412\u4f8b\u53d7\u8bd5\u8005\u65e0\u9700\u673a\u68b0\u901a\u6c14\uff0c\u5e76\u4e14\u5168\u90e8\u5eb7\u590d\u51fa\u9662\uff1b\u5728\u4ec5\u63a5\u53d7\u6807\u51c6\u62a4\u7406\u6cbb\u7597\u768429\u4f8b\u60a3\u8005\u4e2d4\u4f8b\u75c5\u60c5\u53d1\u5c55\u4e3a\u9700\u8981\u673a\u68b0\u901a\u6c14\u7684\u5371\u91cd\u578b\uff0c\u5176\u4e2d3\u4eba\u6b7b\u4ea1\u3002\u8be5\u7814\u7a76\u8bbe\u8ba1\u539f\u4e3a\u4e00\u9879\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\uff0c\u4f46\u7531\u4e8e\u5e72\u7ec6\u80de\u4f9b\u5e94\u4e0d\u8db3\uff0c\u65e0\u6cd5\u6309\u539f\u8ba1\u5212\u5bf9\u53d7\u8bd5\u8005\u8fdb\u884c\u968f\u673a\u5206\u7ec4\uff0c\u56e0\u6b64\u7814\u7a76\u7ed3\u679c\u53d7\u5230\u4e86\u6837\u672c\u91cf\u5c0f\u4e14\u7f3a\u5c11\u968f\u673a\u5316\u7684\u9650\u5236\u3002<\/span>\n <\/section>\n
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\n \u8868\u4e00\u3001\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u65b0\u51a0\u80ba\u708e\u7684\u4e09\u9879\u4e34\u5e8a\u7814\u7a76\u7684\u603b\u7ed3\u548c\u5bf9\u6bd4\u3002<\/span>\n <\/p>\n
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\n *\u7531\u4e8e\u5e72\u7ec6\u80de\u4f9b\u5e94\u4e0d\u8db3\uff0c\u65e0\u6cd5\u6309\u539f\u8ba1\u5212\u8fdb\u884c\u968f\u673a\u5bf9\u7167\u7814\u7a76<\/span>\n <\/section>\n
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\n \u7ec6\u80de\u5916\u6ccc\u4f53\uff08EVS\uff09\u6cbb\u7597\u65b0\u51a0\u80ba\u708e<\/strong><\/span>\n <\/section>\n <\/section>\n
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\n 2021\u5e747\u670814\u65e5\uff0cFDA\u518d\u6b21\u6279\u51c6\u4e86\u6765\u81eaDirect Biologics LLC.\u516c\u53f8\u7684ExoFlo\u2122\u4ea7\u54c1\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u3002\u8fd9\u662f\u81ea\u8fc7\u53bb\u4e00\u5e74\u6765\u8be5\u4ea7\u54c1\u7b2c\u56db\u6b21\u83b7\u5f97FDA\u7684IND\u6279\u51c6\uff0c\u5176\u6cbb\u7597\u8303\u56f4\u6db5\u76d6\uff1a\u91cd\u75c7\u578b\u65b0\u51a0\u80ba\u708e\u3001\u8f7b\u578b\u53ca\u666e\u901a\u578b\u65b0\u51a0\u80ba\u708e\u3001\u6025\u6027\u540e\u65b0\u51a0\u80ba\u708e\u7efc\u5408\u5f81\u3001\u4ee5\u53ca\u975e\u65b0\u51a0\u80ba\u708e\u76f8\u5173\u7684ARDS\u3002<\/span>\n <\/section>\n
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\n $\"3.png\"$ \n <\/p>\n
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\n ExoFlo\u2122\u6cbb\u7597\u91cd\u75c7\u578b\u65b0\u51a0\u80ba\u708e\u53ca\u5f15\u53d1\u7684ARDS\u5df2\u8fdb\u5165\u5168\u56fd\u591a\u4e2d\u5fc3II\u671f\u4e34\u5e8a\u7684\u53d7\u8bd5\u8005\u62db\u52df\u9636\u6bb5\u3002\u8054\u5408\u521b\u59cb\u4eba\u517c\u9996\u5e2d\u6267\u884c\u5b98Mark Adams\u5ba3\u5e03\u201cII\u671f\u8bd5\u9a8c\u5df2\u7ecf\u8fbe\u5230\u4e86\u6570\u4e2a\u5173\u952e\u91cc\u7a0b\u7891\uff0c\u5e76\u5373\u5c06\u5b8c\u6210\u3002\u6211\u4eec\u671f\u5f85\u5206\u4eab\u6211\u4eec\u7684\u6210\u679c\uff0c\u5e76\u5e0c\u671b\u5f88\u5feb\u8fdb\u5165III\u671f\u4e34\u5e8a\u9636\u6bb5\u3002\u201d\n <\/section>\n
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\n \u4f17\u6240\u5468\u77e5\uff0c\u6d3b\u7684\u5e72\u7ec6\u80de\u56e0\u4e3a\u201c\u6d3b\u201d\u800c\u66f4\u6709\u6548\uff0c\u4f46\u540c\u65f6\u4e5f\u56e0\u4e3a\u201c\u6d3b\u201d\u800c\u53d7\u5236\u4e8e\u201c\u6e29\u5ea6\u3001\u8ddd\u79bb\u201d\uff0c\u75ab\u60c5\u7684\u9694\u79bb\u5c31\u66f4\u52a0\u5267\u4e86\u6709\u6548\u5e72\u7ec6\u80de\u5236\u54c1\u7684\u8fd0\u8f93\u548c\u4ea4\u4ed8\u7684\u56f0\u96be\u3002\u667a\u80fd\u5316\u5e8a\u8fb9\u751f\u4ea7\u7cfb\u7edf\uff08Point-of-care Manufacturing Platform\uff09\u5c06\u80fd\u6709\u6548\u89e3\u51b3\u8fd9\u4e00\u6838\u5fc3\u6311\u6218\u3002\u667a\u80fd\u5316\u5e8a\u8fb9\u751f\u4ea7\u7cfb\u7edf\uff08Point-of-care Manufacturing Platform\uff09\u53ef\u4ee5\u66f4\u597d\u7684\u9002\u5e94\u65b0\u51a0\u75ab\u60c5\u7684\u9694\u79bb\u653f\u7b56\uff0c\u66f4\u9ad8\u6548\u3001\u654f\u6377\u5730\u5b9e\u73b0\u6709\u6548\u7684\u5e72\u7ec6\u80de\u4ea7\u54c1\u5411\u4e34\u5e8a\u4ea4\u4ed8\uff0c\u5e76\u4fdd\u8bc1\u5e72\u7ec6\u80de\u4ea7\u54c1\u7684\u5145\u8db3\u4f9b\u5e94\u3002\u6211\u4eec\u671f\u5f85\u5e8a\u8fb9\u667a\u80fd\u751f\u4ea7\u7cfb\u7edf\u5e94\u7528\u4e8e\u5927\u578b\u4e25\u8c28\u7684\u968f\u673a\u5bf9\u7167\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u63d0\u4f9b\u66f4\u5f3a\u5927\u7684\u6570\u636e\u652f\u6301\uff0c\u52a0\u901f\u5e72\u7ec6\u80de\u4ea7\u54c1\u8fdb\u5165\u4e34\u5e8a\u6cbb\u7597\u65b0\u51a0\u75c5\u6bd2\u611f\u67d3\u548c\u80ba\u708e\u3002<\/span>\n <\/section>\n
\n \n <\/section>\n
\n \u53c2\u8003\u6587\u732e<\/span><\/strong>\n <\/section>\n
\n 1. <\/span><\/strong>Li Z, Niu S, Guo B, et al. Stem cell therapy for COVID-19, ARDS and pulmonary fibrosis. Cell Prolif. 2020;53:e12939.<\/span><\/span>\n <\/section>\n
\n 2. <\/span><\/strong>Coronavirus Disease 2019 (COVID-19) Treatment Guidelines. Download from https:\/\/www.covid19treatmentguidelines.nih.gov\/<\/span><\/span>\n <\/section>\n
\n 3. <\/span><\/strong>Leng Z, Zhu R, Hou W, et al. Transplantation of ACE2(-) mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia. Aging Dis. 2020;11(2):216-228. <\/span><\/span>\n <\/section>\n
\n 4. <\/span><\/strong>Shu L, Niu C, Li R, et al. Treatment of severe COVID-19 with human umbilical cord mesenchymal stem cells. Stem Cell Res Ther. 2020;11(1):361. <\/span><\/span>\n <\/section>\n
\n 5. <\/span><\/strong>Lanzoni G, Linetsky E, Correa D, et al. Umbilical cord mesenchymal stem cells for COVID-19 acute respiratory distress syndrome: A double-blind, Phase 1\/2a, randomized controlled trial. Stem Cells Transl Med. 2021 May;10(5):660-673. <\/span><\/span>\n <\/section>\n
\n 6. <\/span><\/strong>https:\/\/directbiologics.com\/press-releases\/<\/span><\/span>\n <\/section>\n<\/section>\n","protected":false},"excerpt":{"rendered":"
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