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**1.\u524d\u8a00<\/strong><\/span><\/p>\n\n\n\n**
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$\"\u5168\u4e16\u754c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6ce8\u518c\u4e34\u5e8a\u8bd5\u9a8c\u9879\u76ee\"$
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**2.\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6ce8\u518c\u7684\u9002\u5e94\u75c7\u975e\u5e38\u5e7f\u6cdb<\/strong><\/span><\/p>\n\n\n\n**
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\u9996\u5148\uff0c\u6211\u4eec\u5728mRNA\u6c34\u5e73\u548c\u86cb\u767d\u6c34\u5e73\u8bc1\u5b9eIGFBP7\u7684\u5728MSCs\u4e2d\u9ad8\u8868\u8fbe\uff1b\u63a5\u7740\u5229\u7528RNA\u5e72\u6270\u6280\u672f\uff0c\u53d1\u73b0IFGBP7\u5177\u6709\u53ef\u5e72\u6270\u7684\u7279\u5f81\uff0c\u8fd9\u5c31\u663e\u793aIGFBP7\u53ef\u4ee5\u4f5c\u4e3a\u5019\u9009\u5206\u5b50\u3002\u5148\u5728\u4f53\u5916\u5b9e\u9a8c\uff0c\u53d1\u73b0 IGFBP7\u5177\u6709\u663e\u8457\u4fc3\u8fdbMSCs\u4ecb\u5bfc\u7684\u514d\u75ab\u8c03\u8282\u7684\u4f5c\u7528\u3002\u63a5\u7740\u5728\u52a8\u7269\u6a21\u578b\uff0c\u6211\u4eec\u91cd\u590d\u51fa\u4f53\u5916\u5b9e\u9a8c\u7684\u7ed3\u679c\u3002\u6211\u4eec\u7684\u7814\u7a76\u8868\u660eIGFBP7\u53ef\u4ee5\u4f5c\u4e3aMSCs\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u76f8\u5173\u7684\u4e00\u4e2a\u6709\u6548\u6027\u8bc4\u4ef7\u6307\u6807\u3002<\/p>\n\n\n\n
**3.\u8ba8\u8bba\uff1a\u521b\u65b0\u79d1\u6280\u6210\u679c\u6784\u5efa\u7ec6\u80de\u6cbb\u7597\u6709\u6548\u6027\u6307\u6807\u8bc4\u4ef7\u4f53\u7cfb<\/span><\/strong><\/p>\n\n\n\n**
\u968f\u7740\u751f\u547d\u79d1\u5b66\u548c\u751f\u7269\u79d1\u6280\u5feb\u901f\u53d1\u5c55\uff0c\u65b0\u7406\u8bba\u3001\u65b0\u5de5\u5177\u3001\u65b0\u68c0\u6d4b\u65b9\u6cd5\u7684\u66f4\u65b0\u8fed\u4ee3\uff0c\u4eba\u7c7b\u7684\u6700\u57fa\u672c\u7279\u5f81\u5c31\u662f\u77e5\u9053\u5982\u4f55\u5229\u7528\u5de5\u5177\u63d0\u9ad8\u6211\u4eec\u7684\u751f\u5b58\u6548\u7387\u3002\u56e0\u6b64\u5982\u4f55\u5c06\u751f\u547d\u79d1\u5b66\u3001\u751f\u7269\u79d1\u6280\u3001\u8ba1\u7b97\u79d1\u5b66\u7b49\u9886\u57df\u4e2d\u7684\u65b0\u5de5\u5177\u5e94\u7528\u5230\u7ec6\u80de\u6cbb\u7597\u7684\u8d28\u91cf\u8bc4\u4ef7\u4e2d\uff1f\u4ee5\u63d0\u5347\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u5e94\u7528\u8f6c\u5316\u6548\u7387\uff0c\u4fdd\u969c\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u6548\u679c\uff0c\u5b9e\u73b0\u79d1\u6280\u521b\u65b0\u6210\u679c\u4e0e\u4e34\u5e8a\u6cbb\u7597\u624b\u6bb5\u7684\u7ed3\u5408\u3002<\/p>\n\n\n\n
**\uff081\uff09\u5229\u7528\u8868\u8fbe\u8c31\u6570\u636e\u7b5b\u9009MSC\u65b0\u6548\u5e94\u5206\u5b50\u7684\u7b56\u7565\u53ef\u884c\u3001\u53ef\u9760<\/span><\/p>\n\n\n\n**
\u6211\u4eec\u5728\u7533\u62a5\u9002\u5e94\u75c7\u8981\u5bf9\u5e94\u76f8\u5e94\u7684\u7ec6\u80de\u4e9a\u578b\uff0c\u5c31\u548c\u6211\u4eec\u8f93\u8840\u4e00\u6837\uff0c\u914d\u597d\u8840\u578b\u3002\u6211\u4eec\u8981\u914d\u597d\u9002\u5e94\u75c7\u7279\u5f02\u6807\u8bb0\uff0c\u4e5f\u5c31\u662fMSCs\u5e94\u8be5\u533a\u5206\u4e0d\u540c\u7684\u4e9a\u578b\uff0c\u800c\u4e0d\u80fd\u201c\u4ec0\u4e48\u90fd\u80fd\u5e72\uff08One-For-All\uff09\u201d\u3002\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u4f5c\u4e3a\u65b0\u836f\u7533\u62a5\u65f6\uff0c\u5b89\u5168\u6709\u6548\u6027\u7684\u6307\u6807\uff0c\u4f60\u8be5\u600e\u4e48\u6784\u5efa\uff1f\u4f5c\u4e3a\u76d1\u7ba1\u90e8\u95e8\uff0c\u5b89\u5168\u6027\u3001\u6709\u6548\u6027\u7684\u6307\u6807\u8be5\u600e\u4e48\u8bc4\u4ef7\uff1f<\/p>\n\n\n\n
MSCs\u5728\u4e34\u5e8a\u5177\u6709\u5e7f\u9614\u7684\u5e94\u7528\u524d\u666f\uff0c\u76f8\u5173\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u53ca\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u7ecf\u8bc1\u5b9e\u67d0\u4e9bMSCs\u5728\u6cbb\u7597\u67d0\u4e9b\u9002\u5e94\u75c7\u662f\u5b89\u5168\u3001\u6709\u6548\u7684\uff1b\u4f46\u5176\u6cbb\u7597\u673a\u5236\u4ecd\u8fdc\u672a\u9610\u660e\u3002\u6211\u4eec\u57fa\u4e8e\u8868\u8fbe\u8c31\u5206\u6790\u6784\u5efa\u7684MSCs\u9002\u5e94\u75c7\u76f8\u5173\u5206\u5b50\u7684\u65b9\u6cd5\u5177\u6709\u53ef\u9760\u6027\uff1b\u57fa\u4e8e\u8868\u8fbe\u8c31\u6570\u636e\u5206\u6790\u65b9\u6cd5\u5c06\u6709\u52a9\u4e8e\u6211\u4eec\u63a2\u8ba8MSCs\u4e0e\u5fae\u73af\u5883\u76f8\u4e92\u5f71\u54cd\u7684\u4f5c\u7528\u673a\u5236\u3001\u9274\u5b9aMSCs\u4e0d\u540c\u4e9a\u578b\u7684\u5bf9\u5e94\u529f\u80fd\u548c\u8c03\u63a7\u673a\u5236\u3002<\/p>\n\n\n\n
**\uff082\uff09 \u5efa\u7acb\u9002\u5408\u4e0d\u540c\u75be\u75c5\u6cbb\u7597\u7684\u7279\u5f02\u6027MSC\u6807\u51c6\uff0c\u5b9e\u73b0\u7ec6\u80de\u7cbe\u51c6\u6cbb\u7597<\/span><\/p>\n\n\n\n**
\u73b0\u884c\u7684\u56fd\u9645\u7ec6\u80de\u6cbb\u7597\u534f\u4f1a\u7684\u6807\u51c6\u662f\u4e00\u4e2a\u901a\u7528\u7684\u6700\u4f4e\u6807\u51c6\uff0c\u53ea\u662f\u8868\u660e\u8fd9\u4e2a\u7ec6\u80de\u662f\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff0c\u5e76\u4e0d\u80fd\u5c06MSCs\u7684\u529f\u80fd\u4e0e\u5176\u7533\u62a5\u7684\u9002\u5e94\u75c7\u8fdb\u884c\u5173\u8054\u3002\u7f3a\u4e4f\u5bf9\u5176\u751f\u7269\u5b66\u529f\u80fd\u7684\u76d1\u6d4b\uff0c\u8fd9\u4e5f\u662f\u5bfc\u81f4MSCs\u6cbb\u7597\u6548\u679c\u4e0d\u7a33\u5b9a\uff0c\u4e43\u81f3\u7814\u7a76\u5931\u8d25\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\u3002\u663e\u7136\uff0c\u76ee\u524d\u8fd9\u4e2a\u901a\u7528\u56fd\u9645\u6807\u51c6\u5df2\u7ecf\u65e0\u6cd5\u6ee1\u8db3MSCs\u4ea7\u54c1\u5ba1\u8bc4\u5ba1\u6279\u7684\u8981\u6c42\u3002<\/p>\n\n\n\n
\u73b0\u5728\u7f8e\u56fdFDA\u63a5\u53d7MSCs\u7533\u62a5\u7684\u65f6\u5019\uff0c\u5df2\u7ecf\u5f00\u59cb\u8981\u6c42\u63d0\u4f9b\u4e0e\u9002\u5e94\u75c7\u76f8\u5173\u7684\u529f\u80fd\u6027\u6307\u6807\u7684\u7814\u7a76\u7ed3\u679c\u4e86\u3002\u90a3\u6211\u4eec\u8fd9\u4e2a\u7814\u7a76\u65b9\u6cd5\u548c\u6210\u679c\u662f\u4e0d\u662f\u53ef\u4ee5\u4e3aMSCs\u56fd\u9645\u6807\u51c6\u7684\u66f4\u65b0\u63d0\u4f9b\u601d\u8def\uff1f\u73b0\u884c\u7684\u56fd\u9645\u7ec6\u80de\u6cbb\u7597\u534f\u4f1a\u5173\u4e8eMSCs\u7684\u8bc4\u4ef7\u6807\u51c6\uff0c\u662f\u4e0d\u662f\u5230\u4e86\u8981\u9002\u5e94\u6027\u8c03\u6574\u7684\u65f6\u5019\u4e86\uff1f<\/p>\n\n\n\n
\u901a\u8fc7\u5927\u6279\u91cf\u7684MSCs\u8868\u8fbe\u8c31\u6570\u636e\u5206\u6790\uff0c\u6211\u4eec\u53ef\u4ee5\u7b5b\u9009\u9002\u5408\u4e0d\u540c\u75be\u75c5\u6cbb\u7597\u7684MSCs\u751f\u7269\u5b66\u6307\u6807\uff0c\u5e76\u5efa\u7acb\u9002\u5408\u4e0d\u540c\u75be\u75c5\u6cbb\u7597\u7684\u7279\u5f02\u6027MSCs\u6807\u51c6\uff0c\u5b9e\u73b0\u7cbe\u51c6\u5316\u6cbb\u7597\u3002<\/p>\n\n\n\n
**\uff083\uff09\u5efa\u7acbMSCs\u5206\u5b50\u6807\u8bb0\u6570\u636e\u5e93\uff0c\u5b9e\u73b0\u4e2a\u4f53\u5316\u6cbb\u7597<\/span><\/p>\n\n\n\n**
\u672a\u6765\u53ef\u4ee5\u8003\u8651\u5efa\u7acb\u5927\u89c4\u6a21\u7684MSCs\u7ec6\u80de\u5e93\uff0c\u5e76\u83b7\u5f97MSCs\u7684\u8868\u8fbe\u8c31\u6570\u636e\u5e93\u3002\u5728\u8fd9\u4e00\u4e2a\u5927\u89c4\u6a21\u5e93\u7684\u57fa\u7840\u4e0a\uff0c\u4e00\u65b9\u9762\uff0c\u6211\u4eec\u53ef\u4ee5\u5c06\u75c5\u4eba\u7684\u4e2a\u4f53\u7279\u5f81\u4e0eMSCs\u4e9a\u578b\u4fe1\u606f\u5e93\u8fdb\u884c\u5339\u914d\uff0c\u7b5b\u9009\u9002\u5408\u4e2a\u4f53\u5e94\u7528\u7684MSCs\u4e9a\u578b\uff1b\u53e6\u4e00\u65b9\u9762\uff0c\u6211\u4eec\u4e5f\u53ef\u4ee5\u5728\u6cbb\u7597\u524d\u63d0\u53d6\u75c5\u4eba\u7684\u4e2a\u4eba\u6807\u672c\uff0c\u5982\u5916\u5468\u8840\uff0c\u5728\u4f53\u5916\u4e0e\u4e0d\u540cMSCs\u4e9a\u578b\u8fdb\u884c\u914d\u5bf9\u7b5b\u9009\uff0c\u4ee5\u6311\u9009\u51fa\u9002\u5408\u4e2a\u4f53\u5e94\u7528\u7684\u6700\u4f73\u7ec6\u80de\u682a\u3002<\/p>\n\n\n\n
\u56e0\u6b64\uff0c\u6211\u4eec\u53ef\u4ee5\u5229\u7528\u8868\u8fbe\u8c31\u6570\u636e\u7b5b\u9009\u5efa\u7acbMSCs\u4e9a\u578b\u5206\u5b50\u5e93\u548c\u6570\u636e\u5e93\uff0c\u4e0d\u4ec5\u4ec5\u662f\u4e3a\u4f01\u4e1a\u63d0\u4f9b\u4e86\u63d0\u5347\u7ec6\u80de\u6cbb\u7597\u65b0\u836f\u7814\u53d1\u6548\u7387\u7684\u65b9\u6cd5\u548c\u8def\u5f84\uff0c\u4e5f\u4e3a\u76d1\u7ba1\u90e8\u95e8\u63d0\u4f9b\u4e86\u4e00\u4e2a\u5f88\u6709\u6548\u7684\u8bc4\u4ef7\u5de5\u5177\u548c\u6307\u6807\u3002<\/p>\n\n\n\n
**4.\u603b\u7ed3\uff1a\u521b\u65b0\u79d1\u6280\u6210\u679c\u63d0\u5347\u7ec6\u80de\u6cbb\u7597\u6548\u679c<\/strong><\/span><\/p>\n\n\n\n**
\u7ec6\u80de\u6cbb\u7597\u662f\u4e2a\u65b0\u5174\u7684\u9886\u57df\uff0c\u5b83\u6709\u5f88\u591a\u6211\u4eec\u8fd8\u4e0d\u592a\u77e5\u6653\u7684\u73af\u8282\uff0c\u6b63\u662f\u56e0\u4e3a\u5f88\u591a\u4e0d\u592a\u77e5\u6653\u7684\uff0c\u4e5f\u4e3a\u6211\u4eec\u7684\u7814\u7a76\u4e5f\u63d0\u4f9b\u4e86\u5f88\u591a\u7684\u7ebf\u7d22\uff0c\u6211\u4eec\u53ef\u4ee5\u5f00\u5c55\u8bb8\u591a\u5177\u6709\u9488\u5bf9\u6027\u7684\u7814\u7a76\uff0c\u63d0\u4f9b\u786e\u5b9a\u7684\u8bc1\u636e\u5728\u56fd\u5bb6\u7ec6\u80de\u6807\u51c6\u9886\u57df\u5f62\u6210\u6211\u4eec\u7684\u8bdd\u8bed\u6743\u3002<\/p>\n\n\n\n
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**1.\u524d\u8a00<\/strong><\/span><\/p>\n\n\n\n**
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\u76ee\u524d\u5728\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\uff08National Institutes of Health, NIH\uff09\u4e34\u5e8a\u6570\u636e\u5e93\uff08ClinicalTrials.gov\uff09\u6ce8\u518c\u7684\uff0c\u4e0e\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u76f8\u5173\u7684\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u6d89\u53ca300\u591a\u79cd\u75be\u75c5\uff0c\u4e0e\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u76f8\u5173\u7684\u4e34\u5e8a\u8bd5\u9a8c\u5c31\u591a\u8fbe\u5230947\u9879, \u5176\u4e2d\u4e9a\u6d32\u5730\u533a\u662f295\u9879\u3002<\/p>\n\n\n\n
$\"\u5168\u4e16\u754c\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6ce8\u518c\u4e34\u5e8a\u8bd5\u9a8c\u9879\u76ee\"$
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**2.\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6ce8\u518c\u7684\u9002\u5e94\u75c7\u975e\u5e38\u5e7f\u6cdb<\/strong><\/span><\/p>\n\n\n\n**
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Clinical Trial\u6ce8\u518c\u7684MSC\u4e34\u5e8a\u8bd5\u9a8c\u7684\u5206\u5e03\u60c5\u51b5<\/figcaption><\/figure><\/div>\n\n\n\n
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\u8fd9\u8bf4\u660e\u5f53\u524d\u5e38\u7528\u7684\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u901a\u7528\u8bc4\u4ef7\u6307\u6807\u4e0d\u80fd\u6ee1\u8db3MSCs\u7814\u7a76\u8fdb\u5c55\u7684\u9700\u6c42\u3002\u76ee\u524d\u901a\u7528\u7684MSCs\u7684\u8bc4\u4ef7\u6307\u6807\u53ea\u8868\u660e\u8fd9\u662f\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff0c\u4f46\u4e0e\u5176\u9700\u8981\u6cbb\u7597\u7684\u5177\u4f53\u7684\u9002\u5e94\u75c7\u5c31\u5f88\u96be\u754c\u5b9a\u3002<\/p>\n\n\n\n
\u6bd4\u5982MSCs\u6709\u4e00\u4e2a\u8bc4\u4ef7\u6307\u6807\u662f\u6210\u8f6f\u9aa8\u6027\uff0c\u4f46\u5982\u679c\u8fd9\u4e00\u6279\u7684MSCs\u662f\u7528\u4e8e\u6cbb\u7597\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u8fd9\u4e00\u9879\u6210\u8f6f\u9aa8\u7684\u7279\u6027\u9274\u5b9a\u662f\u5426\u8fd8\u662f\u5fc5\u987b\u3001\u5173\u952e\u6307\u6807\uff1f<\/p>\n\n\n\n
\u518d\u6bd4\u5982\uff0c\u540c\u4e00\u4e2a\u4f9b\u4f53\u4e0d\u540c\u7ec4\u7ec7\u6765\u6e90\u7684MSCs\uff08\u5982\u9aa8\u9ad3\u3001\u8110\u5e26\u7ec4\u7ec7\u3001\u80ce\u76d8\u8715\u819c\u7ec4\u7ec7\u3001\u7259\u9ad3\u3001\u8102\u80aa\u7ec4\u7ec7\u7b49\uff09\uff0c\u5176\u529f\u80fd\u662f\u5426\u4f1a\u6709\u5dee\u5f02\uff1f\u4e0d\u540c\u4f9b\u4f53\u7684MSCs\u7684\u529f\u80fd\u662f\u5426\u4e0d\u540c\uff1f \u8fd9\u4e9b\u90fd\u662f\u5728\u5f00\u53d1\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5236\u5242\u7684\u7814\u7a76\u8fc7\u7a0b\u4e2d\u4e9f\u5f85\u56de\u7b54\u7684\u95ee\u9898\u3002<\/p>\n\n\n\n
\u53ef\u5851\u6027\uff1aMSC\u529f\u80fd\u7684\u53d1\u6325\u6709\u8d56\u4e8e\u75be\u75c5\u5fae\u73af\u5883\u7684\u201c\u8d4b\u80fd\u201d\uff0c\u800c\u5fae\u73af\u5883\u590d\u6742\u3001\u591a\u6837\uff0c\u5bfc\u81f4MSC\u6cbb\u7597\u6548\u679c\u5b58\u5728\u5dee\u5f02\u3002<\/span><\/p>\n\n\n\n
\u5728\u4e0d\u540c\u7684\u708e\u75c7\u76f8\u5173\u75be\u75c5\u4e2dMSC\u4f5c\u7528\u5b58\u5728\u5dee\u5f02\uff0c\u751a\u81f3\u5728\u540c\u4e00\u75be\u75c5\u7684\u4e0d\u540c\u9636\u6bb5\u5448\u73b0\u51fa\u76f8\u53cd\u7684\u4f5c\u7528\uff0c\u8fd9\u53ef\u80fd\u4e0e\u673a\u4f53\u75c5\u7406\u5fae\u73af\u5883\u76f8\u5173\u3002\u7814\u7a76\u8868\u660eMSC\u514d\u75ab\u8c03\u8282\u4f5c\u7528\u4e0e\u5fae\u73af\u5883\u76f8\u4e92\u4f5c\u7528\uff0c\u4e14\u708e\u75c7\u56e0\u5b50\u7684\u79cd\u7c7b\u4e0e\u6d53\u5ea6\u4e0eMSC\u514d\u75ab\u8c03\u8282\u80fd\u529b\u5bc6\u5207\u76f8\u5173\u3002<\/p>\n\n\n\n
\u6240\u4ee5\uff0c\u6211\u4eec\u5728\u4e34\u5e8a\u4e0a\u600e\u4e48\u6837\u624d\u80fd\u786e\u5b9a\u54ea\u4e00\u79cd\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u9002\u5408\u6cbb\u7597\u67d0\u4e00\u79cd\u7279\u5b9a\u7684\u9002\u5e94\u75c7\uff1f\u5b89\u5168\u6709\u6548\u6cbb\u7597\u8bc4\u4ef7\u4f53\u7cfb\u5982\u4f55\u6784\u5efa\uff1f\u636e\u6b64\uff0c\u6211\u4eec\u63d0\u51fa\u4ee5\u4e0b\u79d1\u5b66\u95ee\u9898\uff1a\u5982\u4f55\u63d0\u5347MSC\u4e34\u5e8a\u6cbb\u7597\u6548\u7387\u2014\u2014\u4e0d\u4ec5\u5b89\u5168\u800c\u4e14\u6709\u6548\uff1f<\/span><\/p>\n\n\n\n
\uff081\uff09\u901a\u8fc7\u67a2\u7ebd\u57fa\u56e0\u7b5b\u9009\u4e0e\u9002\u5e94\u75c7\u76f8\u5173\u7684MSCs<\/span><\/p>\n\n\n\n
\u9664\u7ec6\u80de\u5f62\u6001\u3001\u8868\u9762\u6807\u5fd7\u3001\u5206\u5316\u80fd\u529b\u5916\uff0c\u4ece\u8868\u8fbe\u8c31\u89d2\u5ea6\u6807\u5b9aMSCs\u7684\u751f\u7269\u5b66\u5c5e\u6027\uff0c\u4e3aMSCs\u7ec6\u80de\u5236\u5242\u63d0\u4f9b\u7cbe\u51c6\u8d28\u63a7\u6807\u51c6\u3002\u76ee\u524dMSCs\u7f3a\u4e4f\u751f\u7269\u5b66\u529f\u80fd\u7684\u8bc4\u5224\u6307\u6807\uff1b\u6211\u4eec\u7684\u5206\u6790\u8fd8\u53d1\u73b0\uff0cMSCs\u5bf9\u4e8e\u708e\u75c7\u56e0\u5b50\u523a\u6fc0\uff0c\u5b58\u5728\u4e00\u7cfb\u5217\u5173\u952e\u7684\u67a2\u7ebd\u57fa\u56e0\u3002\u8fd9\u4e9b\u57fa\u56e0\u53c2\u4e0e\u4e86\u514d\u75ab\u6548\u5e94\u7684\u8c03\u63a7\uff0c\u4e5f\u6d89\u53ca\u5e94\u7b54\u6027\u8c03\u6574\u3002\u8fd9\u63d0\u793a\u6211\u4eec\u8fd9\u4e9b\u67a2\u7ebd\u57fa\u56e0\u6216\u8bb8\u53ef\u4ee5\u4f5c\u4e3a\u5206\u5b50\u6807\u5fd7\uff0c\u7b5b\u9009\u6700\u4f73\u6cbb\u7597\u6548\u80fdMSCs\uff0c\u4ee5\u4f7f\u5f97MSCs\u5177\u6709\u66f4\u7a33\u5b9a\u66f4\u663e\u8457\u7684\u4e34\u5e8a\u6cbb\u7597\u6548\u80fd\u3002<\/p>\n\n\n\n
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**3.\u8ba8\u8bba\uff1a\u521b\u65b0\u79d1\u6280\u6210\u679c\u6784\u5efa\u7ec6\u80de\u6cbb\u7597\u6709\u6548\u6027\u6307\u6807\u8bc4\u4ef7\u4f53\u7cfb<\/span><\/strong><\/p>\n\n\n\n**
\u968f\u7740\u751f\u547d\u79d1\u5b66\u548c\u751f\u7269\u79d1\u6280\u5feb\u901f\u53d1\u5c55\uff0c\u65b0\u7406\u8bba\u3001\u65b0\u5de5\u5177\u3001\u65b0\u68c0\u6d4b\u65b9\u6cd5\u7684\u66f4\u65b0\u8fed\u4ee3\uff0c\u4eba\u7c7b\u7684\u6700\u57fa\u672c\u7279\u5f81\u5c31\u662f\u77e5\u9053\u5982\u4f55\u5229\u7528\u5de5\u5177\u63d0\u9ad8\u6211\u4eec\u7684\u751f\u5b58\u6548\u7387\u3002\u56e0\u6b64\u5982\u4f55\u5c06\u751f\u547d\u79d1\u5b66\u3001\u751f\u7269\u79d1\u6280\u3001\u8ba1\u7b97\u79d1\u5b66\u7b49\u9886\u57df\u4e2d\u7684\u65b0\u5de5\u5177\u5e94\u7528\u5230\u7ec6\u80de\u6cbb\u7597\u7684\u8d28\u91cf\u8bc4\u4ef7\u4e2d\uff1f\u4ee5\u63d0\u5347\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u5e94\u7528\u8f6c\u5316\u6548\u7387\uff0c\u4fdd\u969c\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u6548\u679c\uff0c\u5b9e\u73b0\u79d1\u6280\u521b\u65b0\u6210\u679c\u4e0e\u4e34\u5e8a\u6cbb\u7597\u624b\u6bb5\u7684\u7ed3\u5408\u3002<\/p>\n\n\n\n
**\uff081\uff09\u5229\u7528\u8868\u8fbe\u8c31\u6570\u636e\u7b5b\u9009MSC\u65b0\u6548\u5e94\u5206\u5b50\u7684\u7b56\u7565\u53ef\u884c\u3001\u53ef\u9760<\/span><\/p>\n\n\n\n**
\u6211\u4eec\u5728\u7533\u62a5\u9002\u5e94\u75c7\u8981\u5bf9\u5e94\u76f8\u5e94\u7684\u7ec6\u80de\u4e9a\u578b\uff0c\u5c31\u548c\u6211\u4eec\u8f93\u8840\u4e00\u6837\uff0c\u914d\u597d\u8840\u578b\u3002\u6211\u4eec\u8981\u914d\u597d\u9002\u5e94\u75c7\u7279\u5f02\u6807\u8bb0\uff0c\u4e5f\u5c31\u662fMSCs\u5e94\u8be5\u533a\u5206\u4e0d\u540c\u7684\u4e9a\u578b\uff0c\u800c\u4e0d\u80fd\u201c\u4ec0\u4e48\u90fd\u80fd\u5e72\uff08One-For-All\uff09\u201d\u3002\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u4f5c\u4e3a\u65b0\u836f\u7533\u62a5\u65f6\uff0c\u5b89\u5168\u6709\u6548\u6027\u7684\u6307\u6807\uff0c\u4f60\u8be5\u600e\u4e48\u6784\u5efa\uff1f\u4f5c\u4e3a\u76d1\u7ba1\u90e8\u95e8\uff0c\u5b89\u5168\u6027\u3001\u6709\u6548\u6027\u7684\u6307\u6807\u8be5\u600e\u4e48\u8bc4\u4ef7\uff1f<\/p>\n\n\n\n
MSCs\u5728\u4e34\u5e8a\u5177\u6709\u5e7f\u9614\u7684\u5e94\u7528\u524d\u666f\uff0c\u76f8\u5173\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u53ca\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u7ecf\u8bc1\u5b9e\u67d0\u4e9bMSCs\u5728\u6cbb\u7597\u67d0\u4e9b\u9002\u5e94\u75c7\u662f\u5b89\u5168\u3001\u6709\u6548\u7684\uff1b\u4f46\u5176\u6cbb\u7597\u673a\u5236\u4ecd\u8fdc\u672a\u9610\u660e\u3002\u6211\u4eec\u57fa\u4e8e\u8868\u8fbe\u8c31\u5206\u6790\u6784\u5efa\u7684MSCs\u9002\u5e94\u75c7\u76f8\u5173\u5206\u5b50\u7684\u65b9\u6cd5\u5177\u6709\u53ef\u9760\u6027\uff1b\u57fa\u4e8e\u8868\u8fbe\u8c31\u6570\u636e\u5206\u6790\u65b9\u6cd5\u5c06\u6709\u52a9\u4e8e\u6211\u4eec\u63a2\u8ba8MSCs\u4e0e\u5fae\u73af\u5883\u76f8\u4e92\u5f71\u54cd\u7684\u4f5c\u7528\u673a\u5236\u3001\u9274\u5b9aMSCs\u4e0d\u540c\u4e9a\u578b\u7684\u5bf9\u5e94\u529f\u80fd\u548c\u8c03\u63a7\u673a\u5236\u3002<\/p>\n\n\n\n
**\uff082\uff09 \u5efa\u7acb\u9002\u5408\u4e0d\u540c\u75be\u75c5\u6cbb\u7597\u7684\u7279\u5f02\u6027MSC\u6807\u51c6\uff0c\u5b9e\u73b0\u7ec6\u80de\u7cbe\u51c6\u6cbb\u7597<\/span><\/p>\n\n\n\n**
\u73b0\u884c\u7684\u56fd\u9645\u7ec6\u80de\u6cbb\u7597\u534f\u4f1a\u7684\u6807\u51c6\u662f\u4e00\u4e2a\u901a\u7528\u7684\u6700\u4f4e\u6807\u51c6\uff0c\u53ea\u662f\u8868\u660e\u8fd9\u4e2a\u7ec6\u80de\u662f\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff0c\u5e76\u4e0d\u80fd\u5c06MSCs\u7684\u529f\u80fd\u4e0e\u5176\u7533\u62a5\u7684\u9002\u5e94\u75c7\u8fdb\u884c\u5173\u8054\u3002\u7f3a\u4e4f\u5bf9\u5176\u751f\u7269\u5b66\u529f\u80fd\u7684\u76d1\u6d4b\uff0c\u8fd9\u4e5f\u662f\u5bfc\u81f4MSCs\u6cbb\u7597\u6548\u679c\u4e0d\u7a33\u5b9a\uff0c\u4e43\u81f3\u7814\u7a76\u5931\u8d25\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\u3002\u663e\u7136\uff0c\u76ee\u524d\u8fd9\u4e2a\u901a\u7528\u56fd\u9645\u6807\u51c6\u5df2\u7ecf\u65e0\u6cd5\u6ee1\u8db3MSCs\u4ea7\u54c1\u5ba1\u8bc4\u5ba1\u6279\u7684\u8981\u6c42\u3002<\/p>\n\n\n\n
\u73b0\u5728\u7f8e\u56fdFDA\u63a5\u53d7MSCs\u7533\u62a5\u7684\u65f6\u5019\uff0c\u5df2\u7ecf\u5f00\u59cb\u8981\u6c42\u63d0\u4f9b\u4e0e\u9002\u5e94\u75c7\u76f8\u5173\u7684\u529f\u80fd\u6027\u6307\u6807\u7684\u7814\u7a76\u7ed3\u679c\u4e86\u3002\u90a3\u6211\u4eec\u8fd9\u4e2a\u7814\u7a76\u65b9\u6cd5\u548c\u6210\u679c\u662f\u4e0d\u662f\u53ef\u4ee5\u4e3aMSCs\u56fd\u9645\u6807\u51c6\u7684\u66f4\u65b0\u63d0\u4f9b\u601d\u8def\uff1f\u73b0\u884c\u7684\u56fd\u9645\u7ec6\u80de\u6cbb\u7597\u534f\u4f1a\u5173\u4e8eMSCs\u7684\u8bc4\u4ef7\u6807\u51c6\uff0c\u662f\u4e0d\u662f\u5230\u4e86\u8981\u9002\u5e94\u6027\u8c03\u6574\u7684\u65f6\u5019\u4e86\uff1f<\/p>\n\n\n\n
\u901a\u8fc7\u5927\u6279\u91cf\u7684MSCs\u8868\u8fbe\u8c31\u6570\u636e\u5206\u6790\uff0c\u6211\u4eec\u53ef\u4ee5\u7b5b\u9009\u9002\u5408\u4e0d\u540c\u75be\u75c5\u6cbb\u7597\u7684MSCs\u751f\u7269\u5b66\u6307\u6807\uff0c\u5e76\u5efa\u7acb\u9002\u5408\u4e0d\u540c\u75be\u75c5\u6cbb\u7597\u7684\u7279\u5f02\u6027MSCs\u6807\u51c6\uff0c\u5b9e\u73b0\u7cbe\u51c6\u5316\u6cbb\u7597\u3002<\/p>\n\n\n\n
**\uff083\uff09\u5efa\u7acbMSCs\u5206\u5b50\u6807\u8bb0\u6570\u636e\u5e93\uff0c\u5b9e\u73b0\u4e2a\u4f53\u5316\u6cbb\u7597<\/span><\/p>\n\n\n\n**
\u672a\u6765\u53ef\u4ee5\u8003\u8651\u5efa\u7acb\u5927\u89c4\u6a21\u7684MSCs\u7ec6\u80de\u5e93\uff0c\u5e76\u83b7\u5f97MSCs\u7684\u8868\u8fbe\u8c31\u6570\u636e\u5e93\u3002\u5728\u8fd9\u4e00\u4e2a\u5927\u89c4\u6a21\u5e93\u7684\u57fa\u7840\u4e0a\uff0c\u4e00\u65b9\u9762\uff0c\u6211\u4eec\u53ef\u4ee5\u5c06\u75c5\u4eba\u7684\u4e2a\u4f53\u7279\u5f81\u4e0eMSCs\u4e9a\u578b\u4fe1\u606f\u5e93\u8fdb\u884c\u5339\u914d\uff0c\u7b5b\u9009\u9002\u5408\u4e2a\u4f53\u5e94\u7528\u7684MSCs\u4e9a\u578b\uff1b\u53e6\u4e00\u65b9\u9762\uff0c\u6211\u4eec\u4e5f\u53ef\u4ee5\u5728\u6cbb\u7597\u524d\u63d0\u53d6\u75c5\u4eba\u7684\u4e2a\u4eba\u6807\u672c\uff0c\u5982\u5916\u5468\u8840\uff0c\u5728\u4f53\u5916\u4e0e\u4e0d\u540cMSCs\u4e9a\u578b\u8fdb\u884c\u914d\u5bf9\u7b5b\u9009\uff0c\u4ee5\u6311\u9009\u51fa\u9002\u5408\u4e2a\u4f53\u5e94\u7528\u7684\u6700\u4f73\u7ec6\u80de\u682a\u3002<\/p>\n\n\n\n
\u56e0\u6b64\uff0c\u6211\u4eec\u53ef\u4ee5\u5229\u7528\u8868\u8fbe\u8c31\u6570\u636e\u7b5b\u9009\u5efa\u7acbMSCs\u4e9a\u578b\u5206\u5b50\u5e93\u548c\u6570\u636e\u5e93\uff0c\u4e0d\u4ec5\u4ec5\u662f\u4e3a\u4f01\u4e1a\u63d0\u4f9b\u4e86\u63d0\u5347\u7ec6\u80de\u6cbb\u7597\u65b0\u836f\u7814\u53d1\u6548\u7387\u7684\u65b9\u6cd5\u548c\u8def\u5f84\uff0c\u4e5f\u4e3a\u76d1\u7ba1\u90e8\u95e8\u63d0\u4f9b\u4e86\u4e00\u4e2a\u5f88\u6709\u6548\u7684\u8bc4\u4ef7\u5de5\u5177\u548c\u6307\u6807\u3002<\/p>\n\n\n\n
**4.\u603b\u7ed3\uff1a\u521b\u65b0\u79d1\u6280\u6210\u679c\u63d0\u5347\u7ec6\u80de\u6cbb\u7597\u6548\u679c<\/strong><\/span><\/p>\n\n\n\n**
\u7ec6\u80de\u6cbb\u7597\u662f\u4e2a\u65b0\u5174\u7684\u9886\u57df\uff0c\u5b83\u6709\u5f88\u591a\u6211\u4eec\u8fd8\u4e0d\u592a\u77e5\u6653\u7684\u73af\u8282\uff0c\u6b63\u662f\u56e0\u4e3a\u5f88\u591a\u4e0d\u592a\u77e5\u6653\u7684\uff0c\u4e5f\u4e3a\u6211\u4eec\u7684\u7814\u7a76\u4e5f\u63d0\u4f9b\u4e86\u5f88\u591a\u7684\u7ebf\u7d22\uff0c\u6211\u4eec\u53ef\u4ee5\u5f00\u5c55\u8bb8\u591a\u5177\u6709\u9488\u5bf9\u6027\u7684\u7814\u7a76\uff0c\u63d0\u4f9b\u786e\u5b9a\u7684\u8bc1\u636e\u5728\u56fd\u5bb6\u7ec6\u80de\u6807\u51c6\u9886\u57df\u5f62\u6210\u6211\u4eec\u7684\u8bdd\u8bed\u6743\u3002<\/p>\n\n\n\n
\u5927\u5bb6\u90fd\u77e5\u9053\uff0c\u73b0\u5728\u53ef\u80fd\u6bcf\u4e2a\u5730\u65b9\uff0c\u5305\u62ec\u5e7f\u4e1c\u3001\u6d77\u5357\u3001\u4e0a\u6d77\u7b49\u591a\u4e2a\u5730\u65b9\u653f\u5e9c\uff0c\u90fd\u975e\u5e38\u652f\u6301\u7ec6\u80de\u6280\u672f\u548c\u4ea7\u4e1a\u7684\u53d1\u5c55\u3002<\/p>\n\n\n\n
\u6700\u540e\uff0c\u6211\u4ee5\u6df1\u5733\u4e3a\u4f8b\u3002\u8c08\u8c08\u5982\u4f55\u652f\u6301\u4e00\u4e2a\u65b0\u5174\u4ea7\u4e1a\u7684\u53d1\u5c55\u3002\u652f\u6301\u4e00\u4e2a\u65b0\u5174\u4ea7\u4e1a\u7684\u53d1\u5c55\uff0c\u4e0d\u4ec5\u4ec5\u662f\u653f\u7b56\u7684\u652f\u6301\uff0c\u8fd8\u8981\u5728\u6280\u672f\u672c\u8eab\u53d1\u5c55\u903b\u8f91\u548c\u79d1\u5b66\u89c4\u5f8b\u65b9\u9762\u6709\u9488\u5bf9\u6027\u5730\u652f\u6301\u628a\u5173\u3002<\/p>\n\n\n\n
\u6df1\u5733\u662f\u8fd9\u6837\u505a\u7684\uff0c 2013 \u5e74\u5c31\u5c06\u7ec6\u80de\u6280\u672f\u5217\u4e3a\u672a\u6765\u4ea7\u4e1a\u91cd\u70b9\u57f9\u80b2\u53d1\u5c55\uff0c\u5e76\u4e8e2014\u5e74\u8bbe\u7acb\u300a\u6df1\u5733\u5e02\u672a\u6765\u4ea7\u4e1a\u53d1\u5c55\u4e13\u9879\u8d44\u91d1\u300b\u5b9e\u65bd\u201c\u4e2a\u4f53\u5316\u7ec6\u80de\u6cbb\u7597\u2018\u521b\u65b0\u94fe+\u4ea7\u4e1a\u94fe\u2019\u878d\u5408\u4e13\u9879\u201d\uff0c\u8be5\u4e3e\u63aa\u4e0d\u4ec5\u5173\u6ce8\u7ec6\u80de\u6280\u672f\u672c\u8eab\u7684\u7a81\u7834\u4e0e\u653b\u514b\uff0c\u8fd8\u5145\u5206\u5173\u6ce8\u5230\u4e86\u201c\u6280\u672f\u7a81\u7834\u201d\u5230\u201c\u4e34\u5e8a\u5de5\u5177\u201d\u4e2d\u95f4\u8fc7\u7a0b\u7684\u5173\u952e\u73af\u8282\u548c\u80fd\u529b\u5efa\u8bbe\uff0c\u7504\u522b\u51fa\u7ec6\u80de\u4ea7\u4e1a\u94fe\u4e2d\u5173\u952e\u6216\u7f3a\u5931\u73af\u8282\uff0c\u4f5c\u4e3a\u5f25\u8865\u7ec6\u80de\u4ea7\u4e1a\u5173\u952e\u7f3a\u5931\u73af\u8282\u7684\u7ec6\u80de\u8d28\u91cf\u5206\u6790\u68c0\u6d4b\u670d\u52a1\u5e73\u53f0\u2014\u2014\u6210\u7acb\u4e86\u6df1\u5733\u79d1\u8bfa\u533b\u5b66\u68c0\u9a8c\u5b9e\u9a8c\u5ba4\uff0c\u627f\u62c5\u7b2c\u4e09\u65b9\u7684\u7ec6\u80de\u8d28\u91cf\u68c0\u5b9a\u804c\u80fd\uff0c\u4fdd\u969c\u7ec6\u80de\u50a8\u5b58\u548c\u4e34\u5e8a\u7814\u7a76\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002<\/p>\n\n\n\n
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