\n \u5218\u6c90\u82b8<\/span>\n <\/section>\n

\n \u7ec6\u80de\u4ea7\u4e1a\u5173\u952e\u5171\u6027\u6280\u672f\u56fd\u5bb6\u5de5\u7a0b\u7814\u7a76\u4e2d\u5fc3 \u4e3b\u4efb<\/span>\n <\/section>\n

\n \u4e2d\u56fd\uff08\u6df1\u5733\uff09\u7efc\u5408\u5f00\u53d1\u7814\u7a76\u9662 \u7279\u7ea6\u7814\u7a76\u5458<\/span>\n <\/section>\n

\n \u300a\u4e2d\u534e\u7ec6\u80de\u4e0e\u5e72\u7ec6\u80de\u6742\u5fd7\u300b \u526f\u603b\u7f16\u8f91<\/span>\n <\/section>\n

\n \n <\/section>\n

\n \n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n

\n \n <\/section>\n <\/section>\n

\n \n <\/p>\n

\n 2024\u5e74\u7684\u8bfa\u5956\uff0c\u9664\u4e86\u9996\u65e5\u7684\u533b\u5b66\/\u751f\u7406\u5b66\u5956\uff0c\u63a5\u4e0b\u6765\u7684\u7269\u7406\u5956\u548c\u5316\u5b66\u5956\u4e0d\u7ea6\u800c\u540c\u7684\u90fd\u7ed9\u4e86\u4eba\u5de5\u667a\u80fd\u9886\u57df\uff0c\u8fd9\u4e24\u4e2a\u5956\u9879\u7684\u6388\u4e88\u662f\u524d\u65e0\u53e4\u4eba\uff0c\u4f46\u4e0d\u4e00\u5b9a\u662f\u540e\u65e0\u6765\u8005\u7684\u51b3\u5b9a\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u7269\u7406\u5956\u7ed9\u4e86\u666e\u6797\u65af\u987f\u5927\u5b66\u7684John Hopfield\u548c\u591a\u4f26\u591a\u5927\u5b66\u7684Geoffrey Hinton\uff0c\u80af\u5b9a\u4e86\u4e24\u4f4d\u6b65\u5165\u53e4\u7a00\u4e4b\u5e74\u7684\u8001\u6559\u6388\u5e74\u8f7b\u65f6\u201c\u5145\u6ee1\u6ce2\u6298\u201d\u7684\u7814\u7a76\u6210\u679c\uff0c\u4ed6\u4eec\u5e94\u7528\u7269\u7406\u5b66\u5de5\u5177\u53d1\u73b0\u4e86\u4fe1\u606f\u79d1\u6280\u7684\u7814\u7a76\u65b0\u8303\u5f0f\uff0c\u5960\u5b9a\u4e86\u5f3a\u5927\u7684\u673a\u5668\u5b66\u4e60\u7684\u57fa\u7840\u7406\u8bba\uff0c\u4e0d\u65ad\u5f15\u53d1\u5f53\u524d\u7684\u79d1\u5b66\u7814\u7a76\u8303\u5f0f\u6539\u53d8\u4e0e\u5de5\u7a0b\u521b\u65b0\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n $\"\u56fe\u7247\"$ \n <\/p>\n

\n \n <\/p>\n

\n \u5316\u5b66\u5956\u9881\u7ed9\u4e86\u86cb\u767d\u8d28\u8bbe\u8ba1\u548c\u7ed3\u6784\u9884\u6d4bAI\u5de5\u5177\u7684\u53d1\u660e\u4eba\uff0c\u8c37\u6b4cDeepMind\u7684Demis Hassabis\u3001John Jumper\u548c\u534e\u76db\u987f\u5927\u5b66\u7684David Baker\u3002\u8fd9\u9879AI\u5de5\u5177\u57fa\u4e8e\u4eba\u5de5\u795e\u7ecf\u7f51\u7edc\u5f00\u53d1\u51fa\u7528\u4e8e\u9884\u6d4b\u86cb\u767d\u8d28\u7ed3\u6784\u548c\u8bbe\u8ba1\u5168\u65b0\u7684\u86cb\u767d\u8d28\u3002\u5176\u4e2d\uff0c\u8c37\u6b4c\u5f00\u53d1\u7684AlphaFold<\/span>\u83b7\u5f97\u4e862023\u5e74\u76d6\u5c14\u5fb7\u7eb3\u5956\uff0c\u800c\u76d6\u5c14\u5fb7\u7eb3\u5956\u901a\u5e38\u88ab\u8ba4\u4e3a\u662f\u8bfa\u5956\u98ce\u5411\u6807\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n $\"\u56fe\u7247\"$ \n <\/p>\n

\n \n <\/p>\n

\n \u4eba\u5de5\u795e\u7ecf\u7f51\u7edc<\/span>\u7684\u53d1\u660e\uff0c\u6e90\u4e8e\u4e0a\u4e2a\u4e16\u7eaa80\u5e74\u4ee3\u3002Hopfield\u548cHinton\u7ec4\u88c5\u4e86\u4e0d\u540c\u7684\u8ba1\u7b97\u88c5\u7f6e\u6a21\u62df\u4eba\u7c7b\u5927\u8111\u7684\u8ba4\u77e5\u6a21\u5f0f\uff0cHopfield\u53d1\u660e\u4e86\u8bb0\u5fc6\u7f51\u7edc\uff0c\u7528\u4e8e\u50a8\u5b58\u548c\u91cd\u6784\u56fe\u50cf\uff1bHinton\u53d1\u660e\u4e86\u4e00\u79cd\u4ece\u6570\u636e\u96c6\u4e2d\u63d0\u53d6\u7279\u5f81\u7684\u65b9\u6cd5\uff0c\u4ece\u800c\u80fd\u8bc6\u522b\u56fe\u50cf\u4e2d\u5177\u6709\u7279\u5f02\u6027\u7684\u7279\u5f81\u3002\u6b63\u5982\u8bfa\u5956\u59d4\u5458\u4f1a\u4ecb\u7ecd\u7684\u90a3\u6837\uff0cHopfield\u548cHinton\u7684\u5de5\u4f5c\u4e0d\u4ec5\u662f\u63a8\u52a8\u4e86\u7269\u7406\u5b66\u79d1\u7684\u8fdb\u6b65\uff0c\u4e5f\u5bf9\u6211\u4eec\u7684\u65e5\u5e38\u751f\u6d3b\u5e26\u6765\u5de8\u53d8\uff0c\u6bd4\u5982\u4eba\u8138\u8bc6\u522b\u3001\u81ea\u52a8\u7ffb\u8bd1\u7b49\u3002\u540c\u65f6\uff0c\u5316\u5b66\u5956\u7814\u7a76\u6210\u679cAlphaFold\u7b49\u5bf9\u751f\u547d\u79d1\u5b66\u7814\u7a76\u8303\u5f0f\u7684\u6539\u53d8\uff0c\u9a71\u52a8\u7740\u751f\u547d\u79d1\u5b66\u9886\u57df\u7684\u7814\u7a76\u4ece\u8fc7\u53bb\u7684\u201c\u5047\u8bbe-\u5b9e\u9a8c-\u9a8c\u8bc1\u201d\u8bd5\u9519\u6a21\u5f0f\u8f6c\u5411\u4e86\u6570\u636e\u9a71\u52a8\u7684\u65e0\u5047\u8bbe\u7814\u7a76\u8303\u5f0f\uff0c\u6781\u5927\u5730\u7f29\u77ed\u4e86\u751f\u547d\u79d1\u5b66\u9886\u57df\u91cd\u78c5\u6210\u679c\u7684\u201c\u5047\u8bbe-\u9a8c\u8bc1-\u8bd5\u9519-\u518d\u9a8c\u8bc1\u201d\u7684\u603b\u4f53\u7814\u7a76\u5468\u671f\uff0c\u7b80\u5316\u4e86\u751f\u547d\u79d1\u5b66\u7814\u7a76\u5f00\u53d1\u7684\u590d\u6742\u4f53\u7cfb\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n \u4e24\u4e2a\u5956\u9879\u7684\u9881\u53d1\uff0c\u6807\u5fd7\u7740AI\u5df2\u6210\u4e3a\u65b0\u7684\u57fa\u7840\u5b66\u79d1<\/span><\/strong>\u3002\u6211\u56fd\u5373\u5c06\u6b65\u5165\u7b2c\u5341\u4e94\u4e2a\u4e94\u5e74\u89c4\u5212\u671f\uff0c\u57fa\u4e8e\u5316\u5b66\u5956\u5bf9\u7ed3\u6784\u751f\u7269\u5b66\u5e26\u6765\u7684\u8303\u5f0f\u6539\u53d8\uff0c\u4eca\u5e74\u7684\u5956\u9879\u5c06\u4e3a\u6211\u4eec\u90e8\u7f72\u4ea7\u4e1a\u8bbe\u65bd\u4e0e\u4ea7\u4e1a\u91cd\u5927\u516c\u5171\u670d\u52a1\u5e73\u53f0\u53d1\u5c55\u65b0\u8d28\u751f\u4ea7\u529b\u63d0\u4f9b\u4e00\u4e9b\u53c2\u8003\u548c\u501f\u9274\u3002<\/span>\n <\/p>\n

\n \n <\/p>\n

\n $\"\u56fe\u7247\"$ <\/span>\n <\/p>\n

\n \n <\/p>\n

\n
\n
\n
\n \u5b66\u79d1\u878d\u5408\u7684\u80dc\u5229<\/strong><\/span>\n <\/section>\n
\n \n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n
\n \n <\/p>\n
\n \u4eca\u5e742\u4e2a\u5956\u9879\u7684\u6388\u4e88\uff0c\u53ef\u4ee5\u8bf4\u662f\u5b66\u79d1\u878d\u5408\u7684\u80dc\u5229\uff0c\u5145\u5206\u80af\u5b9a\u4e86\u5b66\u79d1\u4ea4\u53c9\u878d\u5408\u7684\u91cd\u8981\u6027\uff0c\u63a8\u52a8\u6211\u4eec\u8fdb\u5165\u4e86\u4e00\u4e2a\u5bf9\u8fc7\u53bb\u7406\u8bba\u7a81\u7834\u9ad8\u6548\u5229\u7528\u7684\u65b0\u65b9\u5f0f\uff0c\u5bf9\u5df2\u6709\u57fa\u7840\u5b66\u79d1\u7684\u5b58\u91cf\u7406\u8bba\u7a81\u7834\u6027\u7684\u8fdb\u884c\u4ea4\u53c9\u878d\u5408\u5f62\u6210\u65b0\u7684\u57fa\u7840\u5b66\u79d1\uff0c\u4ea7\u751f\u65b0\u7684\u7406\u8bba\u7a81\u7834\uff0c\u4e3a\u4eba\u7c7b\u63a2\u7d22\u81ea\u7136\u7684\u5965\u79d8\u63d0\u4f9b\u65b0\u7684\u57fa\u7840\u7406\u8bba\u548c\u65b0\u7684\u7814\u7a76\u5de5\u5177\uff0c\u8fdb\u4e00\u6b65\u62d3\u5bbd\u6211\u4eec\u8ba4\u77e5\u4e16\u754c\u7684\u8fb9\u754c\uff0c\u4ee5\u53ca\u4eba\u7c7b\u53d1\u660e\u521b\u9020\u7684\u80fd\u529b\u3002\u6211\u4eec\u56fd\u5bb6\u7684\u6559\u4e66\u80b2\u4eba\u7684\u7cfb\u7edf\u662f\u5426\u9700\u8981\u4e0e\u65f6\u4ff1\u8fdb\u5730\u521b\u65b0\u5b66\u79d1\u8bbe\u8ba1\uff1f<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u7269\u7406\u5956\u7684\u6210\u679c\uff0c\u4e24\u4f4d\u79d1\u5b66\u5bb6\u57fa\u4e8e\u7269\u7406\u5b66\u4e2d\u7684\u80fd\u91cf\u6982\u5ff5\uff0c\u4e0e\u6570\u5b66\u3001\u8ba1\u7b97\u79d1\u5b66\u548c\u795e\u7ecf\u79d1\u5b66\u7684\u57fa\u7840\u77e5\u8bc6\u878d\u5408\uff0c\u5f00\u53d1\u51faBoltzmann\u7f51\u7edc\u548cHopfield\u7f51\u7edc\u3002\u65b0\u7684\u57fa\u7840\u7406\u8bba\u7a81\u7834\u4ece\u51fa\u73b0\u5230\u5f15\u7206\u4e00\u4e2a\u65b0\u7684\u4ea7\u4e1a\u9886\u57df\u4e5f\u9700\u8981\u591a\u5b66\u79d1\u3001\u591a\u9886\u57df\u7684\u5e76\u884c\u7a81\u7834\u548c\u4ea4\u53c9\u878d\u5408\uff0c\u4eba\u5de5\u795e\u7ecf\u7f51\u7edc\u7684\u8bc6\u522b\u7cbe\u5ea6\u5728\u8d85\u5927\u7b97\u529b\u548c\u9ad8\u8d28\u91cf\u6570\u636e\u96c6\u7684\u53cc\u91cd\u652f\u6491\u4e0b\u624d\u88ab\u4e1a\u754c\u5e7f\u6cdb\u8ba4\u53ef\u4e0e\u63a5\u53d7\uff0c\u4e5f\u5c31\u662f\u8bf4\u201c\u795e\u7ecf\u7f51\u7edc\u8bc6\u522b\u7b97\u6cd5\uff0cGPU\u52a0\u6301\u7684\u7b97\u529b\u4e0e\u9ad8\u8d28\u91cf\u6570\u636e\u96c6\u201d\u4e09\u65b9\u9762\u7684\u5b8c\u7f8e\u878d\u5408\uff0c\u624d\u5f15\u7206\u4e86\u5f53\u4eca\u7684AI\u65b0\u7eaa\u5143\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u83b7\u5f97\u5316\u5b66\u5956\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u6a21\u578b\u2014\u2014AlphaFold\u7684\u53d1\u660e\uff0c\u66f4\u662f\u4f53\u73b0\u4e86\u7ed3\u6784\u751f\u7269\u548c\u8ba1\u7b97\u751f\u7269\u5b66\u79d1\u9886\u57df\u7684\u77e5\u8bc6\u4ece\u91cf\u53d8\u7684\u79ef\u7d2f\u5f15\u53d1\u8d28\u53d8\u7684\u8fed\u4ee3\u8fc7\u7a0b\uff0cHinton\u7684\u795e\u7ecf\u7f51\u7edc\u7684\u4ef7\u503c\u5728\u7b97\u529b\u7a81\u7834\u540e\u88ab\u5e7f\u4e3a\u63a5\u53d7\uff0c\u4e3a\u4e1a\u754c\u63d0\u4f9b\u7684\u65b0\u7684\u7b97\u6cd5\u67b6\u6784\u3002\u4f46\u5982\u679c\u6ca1\u6709\u5168\u7403\u7ed3\u6784\u751f\u7269\u5b66\u5bb6\u5171\u5efa\u7684\u86cb\u767d\u8d28\u6570\u636e\u5e93\uff0c\u57fa\u4e8e\u795e\u7ecf\u7f51\u7edc\u7684AlphaFold\u7684\u8bad\u7ec3\u53ef\u80fd\u5c31\u4e0d\u4f1a\u5982\u6b64\u987a\u5229\uff0c\u8be5\u6570\u636e\u5e93\u5f00\u653e\u5171\u4eab\u4e86200000+\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u6570\u636e\uff0c\u800c\u5176\u4e2d\u7684\u6bcf\u4e00\u4e2a\u86cb\u767d\u8d28\u6570\u636e\u90fd\u51dd\u805a\u4e86\u7ed3\u6784\u751f\u7269\u5bb6\u6570\u5e74\u7684\u201c\u5fc3\u8840\u201d\u3002<\/span>\n <\/p>\n
\n
\n
\n
\n \u5de5\u5177\u7684\u57fa\u7840\u6027\u4f5c\u7528<\/strong><\/span>\n <\/section>\n
\n \n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n
\n \n <\/p>\n
\n \u57fa\u4e8e\u4eba\u5de5\u795e\u7ecf\u7f51\u7edc\u6df1\u5ea6\u5b66\u4e60\u7528\u4e8e\u86cb\u767d\u8d28\u8bbe\u8ba1\u7684\u5de5\u5177Rosetta\u548c\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u7684\u5de5\u5177AlphaFold\uff0c\u5f7b\u5e95\u89e3\u653e\u4e86\u5f53\u524d\u7ed3\u6784\u751f\u7269\u5b66\u201c\u4e25\u91cd\u4f9d\u8d56\u51b7\u51bb\u7535\u955c\u5e73\u53f0\u548c\u535a\u58eb\u751f\u591c\u4ee5\u7ee7\u65e5\u89c2\u5bdf\u201d\u7684\u7814\u53d1\u8303\u5f0f\u548c\u52b3\u52a8\u6295\u5165\u3002\u5e76\u4e14\u4e00\u4e3e\u63a8\u5230\u4e86\u8fc7\u53bb\u6a2a\u6897\u5728\u8fd9\u4e2a\u5b66\u79d1\u53d1\u5c55\u7684\u51e0\u5ea7\u5927\u5c71\uff1a\u91cd\u8d44\u4ea7<\/strong>\uff08\u6279\u91cf\u8d2d\u4e70\u51b7\u51bb\u7535\u955c\u5efa\u7535\u955c\u5e73\u53f0\uff09\uff0c\u5b66\u751f\u591a<\/strong>\uff08\u4e09\u73ed\u5012\u591c\u4ee5\u7ee7\u65e5\u5730\u89c2\u5bdf\uff09\u3001\u4ee5\u53ca\u7814\u7a76\u7ecf\u8d39\u5927<\/strong>\uff08\u652f\u6301\u51b7\u51bb\u7535\u955c\u5e73\u53f0\u8fd0\u884c\uff09\uff0c\u6d88\u9664\u4e86\u7531\u4e8e\u786c\u4ef6\u3001\u7ecf\u8d39\u548c\u4eba\u5458\u4e0d\u8db3\u9020\u6210\u7684\u7814\u7a76\u6210\u679c\uff08\u4e0d\u662f\u79d1\u7814\u6c34\u5e73\u548c\u80fd\u529b\uff09\u7684\u5dee\u8ddd\u3002\u4e00\u4e3e\u5c06\u7ed3\u6784\u751f\u7269\u5b66\u4ece\u8fc7\u53bb\u7684\u8d77\u70b9\u88c5\u5907\u201c\u8d35\u65cf\u201d\u5316\u8fdb\u5316\u5230\u201c\u7b80\u88c5\u201d\u6613\u884c\uff0c\u63a8\u52a8\u4ece\u4e1a\u8005\u8fdb\u5165\u521b\u65b0\u3001\u521b\u9020\u7684\u7ade\u4e89\uff0c\u884c\u4e1a\u7684\u5dee\u8ddd\u5c06\u7531\u7814\u7a76\u80fd\u529b\u51b3\u5b9a\uff0c\u800c\u4e0d\u662f\u7531\u786c\u4ef6\u6295\u5165\u51b3\u5b9a\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n AI\u65b0\u5de5\u5177\u7684\u63a8\u5e7f\u5e94\u7528\uff0c\u9769\u65b0\u4e86\u65b0\u836f\u5f00\u53d1\u7684\u8def\u5f84\u548c\u5468\u671f\uff0c\u65b0\u836f\u5f00\u53d1\u5de5\u4f5c\u5c06\u4ece\u8fc7\u53bb\u7684\u5927\u6d77\u635e\u9488\u822c\u7684\u88c5\u5907\u6295\u5165\u548c\u4eba\u5458\u6295\u5165\u8f6c\u4e3a\u5148\u9a8c\u77e5\u8bc6\u3001\u9ad8\u8d28\u91cf\u7684\u4ea7\u4e1a\u6570\u636e\u96c6\u7684\u79ef\u7d2f\u3002\u5236\u836f\u5de5\u4e1a\u5e38\u8bf4\u768410\u5e74\u300110\u4e2a\u4ebf\u3001\u4e0a\u5343\u4eba\u7814\u53d1\u56e2\u961f\u7684\u65b0\u836f\u5f00\u53d1\u6a21\u5f0f\u5c06\u4f1a\u5f97\u5230\u660e\u663e\u8f6c\u53d8\u3002\u5728\u6570\u636e\u5e93\u3001\u8ba1\u7b97\u8bbe\u65bd\u7b49\u65b0\u578b\u516c\u5171\u670d\u52a1\u5e73\u53f0\u90e8\u7f72\u5b8c\u5584\u7684\u60c5\u51b5\u4e0b\uff0c\u672a\u6765\u4ec5\u9700\u5341\u51e0\u540d\u6216\u51e0\u5341\u540d\u7814\u7a76\u4eba\u5458\u7ec4\u6210\u7684\u201c\u8f7b\u91cf\u201d\u65b0\u836f\u5f00\u53d1\u56e2\u961f\u53ef\u80fd\u5c06\u6210\u4e3a\u751f\u7269\u533b\u836f\u884c\u4e1a\u7684\u5e38\u6001\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u540c\u65f6\uff0c\u65b0\u5de5\u5177\u7684\u51fa\u73b0\u65e0\u7591\u4f1a\u5bf9\u73b0\u6709\u5de5\u5177\u548c\u65b9\u6cd5\u5e26\u6765\u6781\u5927\u7684\u7834\u574f\u6027\uff0c2020\u5e74AlphaFold2\u5728\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u6311\u6218\u8d5b\u4e2d\u80dc\u51fa\u540e\uff0c\u4e3b\u529e\u65b9\u5728\u5927\u8d5b\u7684\u603b\u7ed3\u9648\u8bcd\u4e2d\u5c31\u5ba3\u5e03\u201c\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u96be\u9898\u5df2\u7ecf\u89e3\u51b3\u4e86\uff0c\u5927\u5bb6\u90fd\u56de\u5bb6\u5e76\u6362\u4e2a\u7814\u7a76\u65b9\u5411\u5427\u3002\u201d<\/span>\n <\/p>\n
\n \n <\/p>\n
\n $\"\u56fe\u7247\"$ <\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u4f46\u662f\u4eba\u7c7b\u7684\u53d1\u5c55\u8fdb\u5316\u53f2\u5c31\u662f\u4e00\u90e8\u5de5\u5177\u548c\u6750\u6599\u8fed\u4ee3\u7684\u5386\u53f2\uff0c\u77f3\u5668\u3001\u9752\u94dc\u548c\u94c1\u5668\u7b49\u65f6\u4ee3\uff0c\u6bcf\u4e00\u6b21\u5de5\u5177\u3001\u6750\u6599\u8fed\u4ee3\u6210\u529f\uff0c\u5c31\u662d\u793a\u7740\u4e00\u4e2a\u65b0\u65f6\u4ee3\u7684\u6765\u4e34\uff0c\u800c\u4f34\u968f\u7740\u5de5\u5177\u7684\u8fdb\u6b65\u8fed\u4ee3\uff0c\u6211\u4eec\u8ba4\u77e5\u6781\u5fae\u4e16\u754c\u7684\u80fd\u529b\u4e0d\u65ad\u589e\u5f3a\u3002\u6b64\u5916\uff0c\u57fa\u4e8e\u65b0\u5de5\u5177\u7684\u4f7f\u7528\uff0c\u4eba\u7c7b\u793e\u4f1a\u5bf9\u8d44\u6e90\u7684\u4f7f\u7528\u80fd\u529b\u3001\u5229\u7528\u6548\u7387\u548c\u53d1\u660e\u521b\u9020\u80fd\u529b\u4e5f\u90fd\u5728\u53d1\u751f\u7ffb\u5929\u8986\u5730\u7684\u53d8\u5316\u3002\u65b0\u76845\u5e74\u89c4\u5212\u4e2d\uff0c\u8d44\u52a9\u9886\u57df\u662f\u5426\u9700\u8981\u6db5\u76d6\u5de5\u5177\u7684\u7814\u53d1\uff0c\u5c24\u5176\u662f\u5177\u6709\u53d8\u9769\u4ea7\u4e1a\u53d1\u5c55\u8def\u5f84\u6f5c\u529b\u7684\u65b0\u5de5\u5177\u4e0e\u65b0\u65b9\u6cd5\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n
\n
\n
\n \u6570\u636e\u9a71\u52a8\u7684\u4ea7\u4e1a\u8bbe\u65bd\u2014\u2014\u6c47\u805a\u9ad8\u8d28\u91cf\u6570\u636e\u96c6\u7684\u6570\u636e\u5e93<\/strong><\/span>\n <\/section>\n
\n \n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n
\n \n <\/p>\n
\n AlphaFold\u7684\u83b7\u5956\uff0c\u540c\u65f6\u4e5f\u662f\u4ea7\u4e1a\u57fa\u7840\u8bbe\u65bd\u7684\u80dc\u5229\uff0c\u603b\u7ed3\u4e0b\u6765\u6709\u4e09\u4ef6\u4e8b\u50ac\u751f\u4e86\u4eca\u5e74\u7684\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\u6210\u679c\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u7b2c\u4e00\uff0c\u9ad8\u8d28\u91cf\u7684\u86cb\u767d\u8d28\u6570\u636e\u5e93\uff08Protein Data Bank\uff09\u7684\u5f00\u653e\u5171\u4eab\uff0c\u662f\u4eca\u5e74\u5316\u5b66\u5956\u7684\u57fa\u7840\u652f\u6491<\/span><\/strong>\u3002<\/span><\/strong>\u51e0\u5341\u5e74\u6765\uff0c\u5168\u4e16\u754c\u6570\u5343\u540d\u7684\u79d1\u5b66\u5bb6\uff08\u4e5f\u5305\u62ec\u4e2d\u56fd\u79d1\u5b66\u5bb6\uff09\u4e0a\u4f20\u5e76\u5171\u4eab\u4e86\u5176\u901a\u8fc7\u51b7\u51bb\u7535\u955c\uff0c\u6216\u5c04\u7ebf\u884d\u5c04\u6676\u4f53\u5206\u6790\u7b49\u53d1\u73b0\u7684\u86cb\u767d\u8d28\u5e8f\u5217\uff0c\u4ee5\u53ca\u63d0\u70bc\u7684\u86cb\u767d\u8d28\u6676\u4f53\u7ed3\u6784<\/span>\uff0c\u5efa\u7acb\u4e86\u516c\u5171\u7684\u86cb\u767d\u8d28\u6570\u636e\u5e93\uff0c\u8be5\u9879\u76ee\u7531\u4e00\u4e2a\u56fd\u9645\u79d1\u5b66\u5bb6\u5c0f\u7ec4\u7ba1\u7406\u3002\u53ef\u4ee5\u8bf4\uff0cDeepMind<\/span>\u7528\u4e8e\u8bad\u7ec3AlphaFold\u7684\u6570\u636e\u662f\u57fa\u4e8e\u6210\u5343\u4e0a\u4e07\u7684\u79d1\u5b66\u5bb6\u6bd5\u751f\u5de5\u4f5c\u800c\u6765\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u7531\u6b64\u53ef\u89c1\uff0c\u80fd\u6c47\u805a\u9ad8\u8d28\u91cf\u6570\u636e\u96c6\u7684\u6570\u636e\u8bbe\u65bd\u5c06\u662f\u672a\u6765\u9a71\u52a8\u79d1\u6280\u521b\u65b0\u5e26\u52a8\u4ea7\u4e1a\u521b\u65b0\u7684\u65b0\u578b\u516c\u5171\u670d\u52a1\u5e73\u53f0\uff0c\u771f\u6b63\u5f00\u653e\u5171\u4eab\u7684\u8fd0\u884c\u673a\u5236\u662f\u5176\u53d1\u6325\u4ea7\u4e1a\u8bbe\u65bd\u4f5c\u7528\u7684\u5173\u952e\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u5176\u6b21\uff0c\u63d0\u4f9b\u4e00\u4e2a\u5f00\u653e\u878d\u5408\u3001\u6700\u5927\u5316\u6570\u636e\u5e93\u6548\u7528\u7684\u516c\u5e73\u7ade\u4e89\u5e73\u53f0\uff0c\u5efa\u7acb\u8d77\u201c\u751f\u7269\u5b66\u5bb6\u4e0a\u4f20\u86cb\u767d\u8d28\u7ed3\u6784\u5b8c\u5584\u6269\u5145\u6570\u636e\u5e93\uff0c\u7ed9\u7b97\u6cd5\u8bad\u7ec3\u63d0\u4f9b\u9ad8\u8d28\u91cf\u6570\u636e\u96c6\uff0c\u83b7\u5f97\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u8bbe\u8ba1\u65b0\u5de5\u5177\u201d\u7684\u826f\u6027\u5faa\u73af\u3002<\/span><\/strong>\n <\/p>\n
\n \n <\/p>\n
\n 20\u4e16\u7eaa70\u5e74\u4ee3\uff0cJohn Moult\u8bfb\u535a\u58eb\u65f6\u538c\u5026\u4e86\u751f\u7269\u5b66\u7e41\u7410\u8017\u65f6\u7684\u5b9e\u9a8c\u4e3b\u4e49\u65b9\u6cd5\uff0c\u8f6c\u5411\u4e0d\u65ad\u53d1\u5c55\u7684\u86cb\u767d\u8d28\u8ba1\u7b97\u9886\u57df\uff0c\u7ed9\u7a0b\u5e8f\u63d0\u4f9b\u4e00\u4e9b\u6c28\u57fa\u9178\u4ee5\u751f\u6210\u6b63\u786e\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u3002\u9010\u6e10\u5730\uff0cJohn Moult\u770b\u5230\u4e86\u5b9e\u9a8c\u4e3b\u4e49\u548c\u8ba1\u7b97\u4e3b\u4e49\u878d\u5408\u7684\u53ef\u884c\u6027\uff1a\u5b9e\u9a8c\u4e3b\u4e49\u5de5\u4f5c\u7cbe\u7ec6\u51c6\u786e\u5ea6\u9ad8\u4f46\u7f13\u6162\u8d39\u529b\uff0c\u8ba1\u7b97\u4e3b\u4e49\u901f\u5ea6\u5feb\u4f46\u5374\u4e3a\u865a\u62df\u4e16\u754c\u4f1a\u7ecf\u5e38\u51fa\u9519\u3002\u4e8e\u662f\u57281994\u5e74\uff0cMoult\u53ca\u5176\u540c\u4e8bKrzysztof Fidelis\u8054\u5408\u8bbe\u7acb\u4e00\u9879\u793e\u533a\u79d1\u5b66\u5b9e\u9a8c\uff0c\u53d1\u8d77\u7ed3\u6784\u9884\u6d4b\u5173\u952e\u8bc4\u4f30\uff08the Critical Assessment of Structure Prediction\uff08CASP\uff09 Competition\uff09\uff0c\u6bcf2\u5e74\u4e00\u6b21\u3002\u5c06\u6570\u636e\u5e93\u4e2d\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u4f5c\u4e3a\u4e00\u4e2a\u516c\u5171\u57fa\u51c6\u53c2\u8003\uff0c\u4ee5\u8d5b\u4e8b\u7684\u5f62\u5f0f\uff0c\u5f00\u653e\u5171\u4eab\u540c\u4e00\u6807\u51c6\u6570\u636e\u96c6\uff0c\u5927\u5bb6\u53ef\u4ee5\u5404\u663e\u795e\u901a\u7684\u5c55\u793a\u5176\u6784\u67b6\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u6a21\u578b\uff0c\u7528\u6a21\u578b\u7b97\u6cd5\u7684\u51c6\u786e\u7387\uff0c\u548c\u5f53\u65f6\u4e1a\u754c\u201c\u91d1\u6807\u51c6\u201d\u5f97\u51fa\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u7684\u51c6\u786e\u7387\u4f5c\u5bf9\u6bd4\uff0c\u770b\u8c01\u7684\u51c6\u786e\u6027\u9ad8\u3002\u81f3\u4eca\u5df2\u6301\u7eed\u4e8620\u591a\u5e74\uff0c\u901a\u8fc7\u5206\u4eab\u4ee3\u7801\u548c\u6280\u672f\uff0c\u4ee5\u53cb\u597d\u7ade\u4e89\u7684\u5f62\u5f0f\uff0c\u671d\u7740\u89e3\u51b3\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u7684\u76ee\u6807\u524d\u8fdb\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u9996\u5148\u53c2\u8d5b\u7684\u662fBaker\u7684Rosetta<\/span>\uff0c\u6210\u4e3a1998\u5e74\u7684\u201c\u5fc5\u80dc\u4e4b\u4eba\u201d\u3002\u671f\u95f4\u53d1\u751f\u4e86\u5171\u540c\u8fdb\u5316\u6982\u5ff5\u7684\u91cd\u5927\u7a81\u7834\uff0cRosetta\u57282014\u5e74\u751f\u6210\u4e862\u4e2a\u7ed3\u6784\u975e\u5e38\u51c6\u786e\u7684\u86cb\u767d\u8d28\uff0c\u4ee5\u81f3\u4e8e\u5f53\u65f6\u7684\u8bc4\u5ba1\u4e13\u5bb6\u90fd\u4ee5\u4e3aBaker\u5b8c\u5168\u89e3\u51b3\u4e86\u86cb\u767d\u8d28\u6298\u53e0\u7684\u95ee\u9898\u3002\u5230\u4e862018\u5e74\uff0cAlphaFold\u9996\u6b21\u53c2\u8d5b\u5c31\u53d6\u5f97\u4ee4\u4eba\u60ca\u53f9\u768460\u5206\uff08\u8fc7\u53bb24\u5e74\uff0c\u5e73\u5747\u53c2\u8d5b\u5f97\u5206\u4e0d\u8d85\u8fc740\u5206\uff0c\u6ee1\u5206100\u5206\uff09\uff1b2\u5e74\u540e\u76842020\u5e74\uff0cAlphaFold2\u53c2\u8d5b\uff0c\u5b8c\u80dc\u6240\u6709\u53c2\u8d5b\u961f\u624b\u3002\u4e8e\u662f\u5c31\u6709\u4e86\u8d5b\u540e\u4e3b\u529e\u65b9\u90a3\u756a\u201c\u5927\u5bb6\u56de\u53bb\u8f6c\u884c\u201d\u7684\u603b\u7ed3\u9648\u8bcd\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u6700\u540e\uff0c\u884c\u4e1a\u4e3a\u589e\u52a0\u6570\u636e\u5e93\u4e2d\u7684\u86cb\u767d\u8d28\u79cd\u7c7b\u4ee5\u53ca\u591a\u6837\u6027\u6240\u505a\u7684\u5404\u79cd\u52aa\u529b\uff1a\u5728\u5efa\u7acb\u6570\u636e\u5e93\u4e4b\u521d\uff0c\u5c31\u786e\u5b9a\u201c\u5f00\u653e\u5171\u4eab\u201d\u7684\u57fa\u8c03\uff0c\u6240\u6709\u7684\u57fa\u56e0\u5e8f\u5217\u5f00\u653e\uff0c\u6240\u6709\u7684\u7ed3\u6784\u5f00\u653e<\/span><\/strong>\u3002\u6570\u5341\u5e74\u7684\u65f6\u95f4\u91cc\uff0c\u5728\u6570\u636e\u5e93\u7684\u57fa\u7840\u4e0a\uff0c\u884c\u4e1a\u901a\u8fc7CASP\u76f8\u4e92\u5b66\u4e60\uff0c\u5efa\u7acb\u8d77\u826f\u597d\u7684\u6570\u636e\u5171\u4eab\u6587\u5316\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u4e3a\u4e86\u63a8\u52a8\u4ee3\u7801\u7684\u5f00\u653e\u5171\u4eab\uff0cBaker(2024\u5e74\u5316\u5b66\u5956\u83b7\u5f97\u8005)\u7684\u5b9e\u9a8c\u5ba4\u57282021\u5e74\u516c\u5e03\u4e86\u5176\u540d\u4e3aRoseTTAFold\u7684\u4ee3\u7801\uff0c\u968f\u540eDeepMind\u4e5f\u5171\u4eab\u4e86\u5176\u4ee3\u7801\u548c\u6839\u636e\u8be5\u6a21\u578b\u9884\u6d4b\u76842.14\u4ebf\u4e2a\u86cb\u767d\u8d28\u7ed3\u6784\uff0c\u8fdb\u4e00\u6b65\u6269\u5927\u4e86AlphaFold\u7684\u5f71\u54cd\uff0c\u5f00\u521b\u4e86\u201c\u4eba\u4eba\u4e3a\u6211\uff0c\u6211\u4e3a\u4eba\u4eba\u201d\u7684\u65b0\u53d1\u5c55\u6a21\u5f0f\uff1a\u6709\u4e86AlphaFold\u6570\u636e\u5e93\uff0c\u5927\u5bb6\u53ef\u4ee5\u641c\u7d22\u6784\u9020\u5e76\u5f97\u5230\u57fa\u4e8e\u4efb\u4f55\u5355\u5143\u6216\u5e8f\u5217\u7684\u86cb\u767d\u8d28\u7ed3\u6784\uff0c\u5373\u4fbf\u662fAlphaFold\u6570\u636e\u5e93\u4e2d\u4e0d\u5b58\u5728\u7684\u7ed3\u6784\uff0c\u7814\u7a76\u4eba\u5458\u4e5f\u53ef\u4ee5\u5c06\u5176\u63d2\u5165\u6a21\u578b\u4e2d\uff0c\u901a\u8fc7AlphFold\u7684\u4ee3\u7801\u8f7b\u6613\u5f97\u5230\u7ed3\u6784\u9884\u6d4b\u3002\u800c\u5171\u4eab\u4e86\u7b97\u6cd5\u4ee3\u7801\u548c\u5176\u9884\u6d4b\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u6570\u636e\u7684\u56e2\u961f\u5728\u5176\u53d1\u5e03AlphaFold2\u7684\u56db\u5e74\u540e\u4fbf\u83b7\u5f97\u8bfa\u8d1d\u5c14\u5956\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u867d\u7136\uff0c\u5728\u4e0a\u4f20\u53d1\u73b0\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u65f6\uff0c\u7ed3\u6784\u751f\u7269\u5b66\u5bb6\u4eec\u81ea\u5df1\u4e5f\u6ca1\u6709\u60f3\u5230\u4f1a\u6709\u8fd9\u4e48\u4e00\u5929\uff0c\u4e0a\u4f20\u8fdb\u6570\u636e\u5e93\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u6570\u636e\u4f1a\u88ab\u4eba\u201c\u7ffb\u8bd1\u201d\u6210\u4ee3\u7801\uff0c\u901a\u8fc7\u673a\u5668\u5b66\u4e60\u7b97\u6cd5\u5904\u7406\uff0c\u7528\u4e8e\u9884\u6d4b\u65b0\u7684\u86cb\u767d\u8d28\u7ed3\u6784\uff0c\u5e76\u8bbe\u8ba1\u51fa\u65b0\u7684\u86cb\u767d\u8d28\u7ed3\u6784\u3002\u56e0\u6b64\uff0c\u4eca\u5e74\u7684\u5956\u9879\u4e0d\u4ec5\u662f\u7ad9\u5728\u5de8\u4eba\u7684\u80a9\u8180\u4e0a\uff0c\u800c\u662f\u5728\u5b8c\u5584\u7684\u6570\u636e\u8bbe\u65bd\u57fa\u7840\u4e0a\uff0c\u7ad9\u5728\u4e86\u5168\u4e16\u754c\u7ed3\u6784\u751f\u7269\u5b66\u5bb6\u4eec\u8d85\u5927\u89c4\u6a21\u6210\u679c\u91d1\u5b57\u5854\u7684\u9876\u7aef\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n
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\n \u8ba8\u8bba<\/strong><\/span>\n <\/section>\n
\n \n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n
\n \n <\/p>\n
\n \u4e0a\u4e2a\u4e16\u7eaa\uff0c\u5b66\u754c\u63a8\u52a8\u653f\u5e9c\u90e8\u7f72\u4e86\u7ecf\u7531\u5b9e\u9a8c\u4e3b\u4e49\u65b9\u6cd5\u83b7\u5f97\u7684\u86cb\u767d\u8d28\u6570\u636e\u5e93\uff0c\u5b55\u80b2\u50ac\u751f\u4e86\u7ed3\u6784\u751f\u7269\u5b66\u9886\u57df\u7684\u65b0\u6280\u672f\u548c\u65b0\u65b9\u6cd5\uff0c\u76ee\u524d\u8fd9\u4e9b\u65b0\u6280\u672f\u5df2\u7ecf\u8db3\u591f\u5f3a\u5927\uff0c\u4e0d\u4ec5\u62ff\u4e86\u8bfa\u8d1d\u5c14\u5956\uff0c\u8fd8\u5c06\u5f15\u53d1\u5236\u836f\u5de5\u4e1a\u7684\u4ea7\u4e1a\u53d8\u9769\uff0cAI\u9a71\u52a8\u7684\u836f\u7269\u8bbe\u8ba1\u548c\u5f00\u53d1\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u901a\u5e38\uff0c\u57fa\u7840\u6280\u672f\u51b3\u5b9a\u4e86\u5177\u4f53\u4ea7\u54c1\u7684\u5f00\u53d1\u65b9\u5411\uff0c\u800c\u7ade\u4e89\u6027\u6280\u672f\u51b3\u5b9a\u4e86\u4e0b\u6e38\u5e02\u573a\u5bb9\u91cf\u7684\u5927\u5c0f\u3002\u653f\u5e9c\u652f\u6301\u4ea7\u4e1a\u516c\u5171\u8bbe\u65bd\u4e0e\u57fa\u7840\u7814\u7a76\uff0c\u63a8\u52a8\u6210\u679c\u9ad8\u6548\u8f6c\u5316\uff0c\u9f13\u52b1\u4e0b\u6e38\u7ade\u4e89\u6027\u6280\u672f\u7684\u591a\u5143\u53d1\u5c55\uff0c\u4ee5\u5f62\u6210\u6709\u5229\u4e8e\u4e2a\u4eba\u548c\u7ecf\u6d4e\u793e\u4f1a\u53d1\u5c55\u7684\u91cd\u78c5\u4ea7\u54c1\uff0c\u751a\u81f3\u4ea7\u751f\u4e00\u4e2a\u5168\u65b0\u7684\u86cb\u767d\u8d28\u8bbe\u8ba1\u4ea7\u4e1a\u3002\u5f00\u653e\u5171\u4eab\u7684\u4ea7\u4e1a\u8bbe\u65bd\u5b55\u80b2\u65b0\u7684\u57fa\u7840\u6027\u6280\u672f\uff0c\u65b0\u7684\u57fa\u7840\u6027\u6280\u672f\u50ac\u751f\u4e86\u4e0b\u6e38\u7ade\u4e89\u6027\u6280\u672f\u7684\u767e\u82b1\u9f50\u653e\uff0c\u5176\u5b9e\u5c31\u662f\u6211\u56fd\u653f\u5e9c\u62a5\u544a\u4e2d\u63d0\u5230\u201c\u79d1\u6280\u521b\u65b0\u5e26\u52a8\u4ea7\u4e1a\u521b\u65b0\u201d\u7684\u53d1\u5c55\u65b0\u8def\u5f84\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u8ba1\u7b97\u4e3b\u4e49\u8005\u5c3d\u53ef\u80fd\u5bf9\u5f53\u524d\u5df2\u6709\u7684\u86cb\u767d\u8d28\u5e8f\u5217\u548c\u7ed3\u6784\u5e93\u4e2d\u7684\u6570\u636e\u8fdb\u884c\u9ad8\u6548\u5229\u7528\uff0c\u8fd9\u5bf9\u5e26\u52a8\u5b9e\u9a8c\u4e3b\u4e49\u8005\u4ea7\u751f\u65b0\u7684\u9ad8\u8d28\u91cf\u5b9e\u9a8c\u6570\u636e\u4e5f\u81f3\u5173\u91cd\u8981\uff0c\u800c\u65b0\u7684\u6570\u636e\u8fdb\u800c\u53c8\u63a8\u52a8\u4e86AI\u7b97\u6cd5\u7684\u8fed\u4ee3\uff1a\u751f\u7269\u5b66\u5bb6\u5c06\u4ece\u5b9e\u9a8c\u4e2d\u53d1\u73b0\u7684\u86cb\u767d\u8d28\u4e0a\u4f20\u81f3\u86cb\u767d\u8d28\u6570\u636e\u5e93\uff0c\u6570\u636e\u5e93\u4e2d\u9ad8\u8d28\u91cf\u7684\u6570\u636e\u96c6\u8bad\u7ec3AI\u7b97\u6cd5\uff0c\u5f62\u6210\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u548c\u8bbe\u8ba1\u7684\u65b0\u5de5\u5177\uff0cAI\u65b0\u5de5\u5177\u8fdb\u4e00\u6b65\u5f15\u53d1\u4ea7\u751f\u65b0\u6210\u679c\u3001\u65b0\u5e94\u7528\u548c\u65b0\u6570\u636e\uff0c\u53cd\u8fc7\u6765\u53c8\u4fc3\u8fdb\u4e86\u5de5\u5177\u7684\u8fdb\u5316\u3001\u8fed\u4ee3\uff0c\u5faa\u73af\u5f80\u590d\uff0c\u4e0d\u65ad\u8fdb\u6b65\u3002<\/span>\n <\/p>\n
\n \n <\/p>\n
\n \u4e0d\u8fc7\uff0c\u867d\u7136\u4eca\u5e74\u7684\u5316\u5b66\u5956\u5bf9\u7ed3\u6784\u751f\u7269\u5b66\u9886\u57df\u5df2\u7ecf\u5f62\u6210\u4e86\u9769\u547d\u6027\u7684\u5f71\u54cd\uff0c\u4f46\u5728\u751f\u547d\u79d1\u5b66\u9886\u57df\uff0c\u7ed3\u6784\u751f\u7269\u5b66\u53ea\u662f\u5176\u4e2d\u7684\u4e00\u4e2a\u5b66\u79d1\uff0c\u751f\u547d\u79d1\u5b66\u9886\u57df\u7684\u5176\u4ed6\u9886\u57df\u4e5f\u4f1a\u4ea7\u751f\u65b0\u7684\u5177\u6709\u7834\u574f\u6027\u7684AI\u5de5\u5177\u5417\uff1f\u4f1a\u6709\u65b0\u7684\u5929\u624d\u56e2\u961f\u548c\u4e16\u754c\u7ea7\u7684\u516c\u53f8\u51fa\u73b0\u5417\uff1f\u6bd5\u7adf\uff0c\u4eca\u5e74\u7269\u7406\u5b66\u5956\u4eba\u5de5\u667a\u80fd\u5960\u57fa\u6027\u7684\u6210\u679c\u5728\u751f\u547d\u79d1\u5b66\u548c\u751f\u7269\u6280\u672f\u9886\u57df\u7684\u91cd\u5927\u5e94\u7528\u624d\u521a\u5f00\u59cb\u5462\uff01\u8ba9\u6211\u4eec\u671f\u5f85\u7740\u540e\u6709\u4e2d\u56fd\u7684\u6765\u8005\uff01<\/span>\n <\/p>\n <\/section>\n
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\n \n <\/p>\n
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\n \u76f8\u5173\u9605\u8bfb<\/strong><\/span>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n
\n
\n
\n AlphaFold\u2014\u6570\u636e\u9a71\u52a8\u7684\u65b0\u578b\u4ea7\u4e1a\u516c\u5171\u670d\u52a1\u5e73\u53f0<\/a>\n <\/p>\n
\n \n <\/p>\n
\n HGP20\u5e74\uff0c\u5de5\u4e1a\u81ea\u52a8\u5316\u5bf9\u79d1\u6280\u4ea7\u4e1a\u7684\u5960\u57fa\u6027\u4f5c\u7528<\/a>\n <\/p>\n
\n \n <\/p>\n
\n \u673a\u5668\u5b66\u4e60\u53ca\u81ea\u52a8\u5316\u5e94\u5bf9CGT\u5546\u4e1a\u5316\u751f\u4ea7\u7684\u6311\u6218<\/a>\n <\/p>\n <\/section>\n <\/section>\n <\/section>\n
\n \n <\/section>\n <\/section>\n <\/section>\n
\n
\n \n <\/p>\n
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\n \u5f80\u671f\u7cbe\u9009\u4e00<\/strong><\/span>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n
\n
\n
\n
\n 2021\u5e74\u20142023\u5e74<\/span>\n <\/p>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n
\n
\n
\n
\n <\/section>\n <\/section>\n <\/section>\n
\n
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\n
\n \u70b9\u51fb\u67e5\u770b\u66f4\u591a>>\u6c90\u82b8\u89c2\u70b9<<<\/span><\/a>\n <\/p>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n
\n
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\n
\n \u5f80\u671f\u7cbe\u9009\u4e8c<\/strong><\/span>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n \n
\n
\n
\n 2019\u5e74\u2014\u20142020<\/span>\n <\/p>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n <\/section>\n
\n
\n
\n
\n <\/section>\n <\/section>\n <\/section>\n
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\n \u6c90\u82b8\u89c2\u70b9(1)|\u8fd0\u52a8\u4f7f\u4eba\u5e74\u8f7b\u5417\uff1f<\/span><\/span><\/span><\/a>\n <\/p>\n
\n \u6c90\u82b8\u89c2\u70b9(2)|\u4ece\u795e\u7ecf\u751f\u7406\u5b66\u89d2\u5ea6\u770b\u516c\u5171\u536b\u751f\u51b3\u7b56\u96be\u9898\uff1a\u8682\u8681\u8fd8\u662f\u86b1\u8722\uff1f<\/a>\n <\/p>\n
\n \u6c90\u82b8\u89c2\u70b9(3)|\u7f8e\u56fd\u75ab\u60c5\u9632\u63a7\u7a97\u53e3\u9519\u5931\u7684\u542f\u53d1\uff1a \u7ba1\u7406\u4e2d\u7684\u9632\u5fae\u675c\u6e10<\/span><\/a>\n <\/p>\n
\n \u6c90\u82b8\u89c2\u70b9(4)|ASCO2020\u5e74\u4f1a\u6982\u8981<\/a>\n <\/p>\n
\n \u6c90\u82b8\u89c2\u70b9(5)|\u6539\u53d8\u4e16\u754c\u7684\u751f\u7269\u9769\u547d<\/a>\n <\/p>\n
\n \u6c90\u82b8\u89c2\u70b9(6)|\u65b0\u51a0\u75c5\u6bd2\u662f\u5982\u4f55\u653b\u9677\u4eba\u4f53\u514d\u75ab\u7cfb\u7edf\u7684\uff1f<\/span><\/a>\n <\/p>\n
\n \u6c90\u82b8\u89c2\u70b9(7)|\u5f53\u8d44\u6e90\u4e0d\u8db3\u65f6\uff0c\u53ef\u80fd\u7f3a\u7684\u4e0d\u662f\u8d44\u6e90\u672c\u8eab\uff0c\u800c\u662f\u601d\u8def<\/a>\n <\/p>\n
\n \u6c90\u82b8\u89c2\u70b9(8)| \u7ec6\u80de\u4ea7\u4e1a\u65b0\u57fa\u5efa\u2014\u2014\u201c1\u5e931\u4e2d\u5fc31\u5e73\u53f0\u201d\u56fd\u5bb6\u7f51\u7edc<\/span><\/a>\n <\/p>\n
\n \u6c90\u4e91\u89c2\u70b9(9)|COVID-19\u6311\u6218\u7684\u662f\u514d\u75ab\u529b \u662f\u5426\u201c\u53ec\u80fd\u6218\u3001\u6218\u5fc5\u80dc\u201d<\/span><\/a>\n <\/p>\n
\n \u6c90\u4e91\u89c2\u70b9(10)|\u7f8e\u56fd\u516c\u5171\u536b\u751f\u670d\u52a1\u90e8\u961f\u4ecb\u7ecd<\/span><\/a>\n <\/p>\n
\n \u6c90\u4e91\u89c2\u70b9(11)|<\/span>\u5982\u4f55\u7528\u5927\u89c4\u6a21\u6807\u51c6\u5316\u6d41\u7a0b\u5b9e\u73b0\u4e2a\u4f53\u5316\u6cbb\u7597<\/span><\/a>\n <\/p>\n
\n \u6c90\u82b8\u89c2\u70b9<\/span>(12)<\/span>| \u75ab\u60c5\u542f\u793a\uff1a\u4e0b\u6b21\u75ab\u60c5\uff0c\u6211\u4eec\u5982\u4f55\u5e94\u5bf9\uff1f<\/span><\/a>\n <\/p>\n
\n \u6c90\u82b8\u89c2\u70b9<\/span>(13)<\/span>| \u603b\u4e66\u8bb0\u70b9\u540d\u7684\u5e72\u7ec6\u80de\u5982\u4f55\u7528\u4e8e\u65b0\u51a0\u80ba\u708e\u6cbb\u7597\uff1f<\/span><\/a>\n <\/p>\n
\n \u6c90\u82b8\u89c2\u70b9<\/span>(14)<\/span>| \u7d27\u6025\u72b6\u6001\u4e0b\uff0c\u4f53\u6064\u6cbb\u7597\u7684\u524d\u63d0\u6761\u4ef6\u662f\u4ec0\u4e48\uff1f<\/span><\/a>\n <\/p>\n
\n \u6c90\u82b8\u89c2\u70b9<\/span>(15)<\/span>| WHO\u8ba4\u4e3a\u65b0\u51a0\u75ab\u60c5\u8fd8\u4e0d\u7b26\u5408\u5927\u6d41\u884c\u201c\u8513\u5ef6\u56fd\u754c\u201d\u7684\u7279\u5f81<\/span><\/a>\n <\/p>\n
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